360045-11-0Relevant articles and documents
Deprotometalation-iodolysis and direct iodination of 1-arylated 7-azaindoles: Reactivity studies and molecule properties
Bentabed-Ababsa, Ghenia,Dorcet, Vincent,Fajloun, Ziad,Halauko, Yury S.,Hamze, Monzer,Ivashkevich, Oleg A.,Matulis, Vadim E.,Messaoud, Mohamed Yacine Ameur,Mongin, Florence,Roisnel, Thierry
, (2021/10/26)
Five protocols were first compared for the copper-catalyzed C-N bond formation between 7-azaindole and aryl/heteroaryl iodides/bromides. The 1-arylated 7-azaindoles thus obtained were subjected to deprotometalation-iodolysis sequences using lithium 2,2,6,
Copper(I) Oxide/N,N′-Bis[(2-furyl)methyl]oxalamide-Catalyzed Coupling of (Hetero)aryl Halides and Nitrogen Heterocycles at Low Catalytic Loading
Pawar, Govind Goroba,Wu, Haibo,De, Subhadip,Ma, Dawei
supporting information, p. 1631 - 1636 (2017/05/22)
An easily prepared oxalic diamide is a powerful ligand for the copper-catalyzed coupling of aryl halides with nitrogen heterocycles. Only 1–2 mol% each of copper(I) oxide and N,N′-bis[(2-furyl)methyl]oxalamide (BFMO) are needed to form N-arylation products under mild conditions. More than 10 different types of nitrogen heterocycles are compatible with these conditions, thereby giving the corresponding N-arylation products. (Figure presented.).
Iron complex-catalyzed N-arylation of pyrazoles under aqueous medium
Lee, Hang Wai,Chan, Albert S.C.,Kwong, Fuk Yee
experimental part, p. 5868 - 5871 (2010/01/11)
Commercially available FeCl3·6H2O with conformationally rigid diamine ligand is a highly effective catalyst for N-arylation of pyrazoles using aryl and heteroaryl iodides. It is notable to show that this complex is tolerable under aqueous medium and particularly the whole reaction utilizes water as the sole solvent without any additional organic co-solvents and surfactants. Attempted study using other nitrogen nucleophiles is described. This newly developed system provides an alternative protocol to Cu- and Pd-catalyzed N-arylation reactions.
