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4-(4-Fluorophenoxy)phenylboronic acid, with the chemical formula C12H9BFO2, is a boronic acid derivative characterized by the presence of aromatic phenyl rings. It is known for its chemical stability and reactivity, featuring both a fluorine atom and boronic acid functionalities. 4-(4-Fluorophenoxy)phenylboronic acid is typically found as a light yellow to white solid powder. It is widely used in synthetic chemistry, particularly in Suzuki-Miyaura cross-coupling reactions, which are crucial for the production of pharmaceuticals and biologically active compounds. Additionally, it plays a role in the manufacturing of organic light-emitting diodes (OLEDs). Due to its potential to cause eye and skin irritation, it is essential to handle and use this chemical with appropriate protective gear.

361437-00-5

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361437-00-5 Usage

Uses

Used in Pharmaceutical Industry:
4-(4-Fluorophenoxy)phenylboronic acid is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to participate in Suzuki-Miyaura cross-coupling reactions. These reactions facilitate the formation of carbon-carbon bonds, which are essential for constructing complex molecular structures found in many drugs.
Used in Organic Synthesis:
In the field of organic synthesis, 4-(4-Fluorophenoxy)phenylboronic acid is employed as a reagent for the preparation of biologically active compounds. Its reactivity in cross-coupling reactions allows for the creation of diverse molecular structures with potential applications in medicine and other fields.
Used in OLED Manufacturing:
4-(4-Fluorophenoxy)phenylboronic acid is used as a precursor material in the production of organic light-emitting diodes (OLEDs). Its incorporation into the OLED structure can influence the device's performance, such as brightness, efficiency, and color characteristics, making it a valuable component in the development of advanced display technologies.

Check Digit Verification of cas no

The CAS Registry Mumber 361437-00-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,1,4,3 and 7 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 361437-00:
(8*3)+(7*6)+(6*1)+(5*4)+(4*3)+(3*7)+(2*0)+(1*0)=125
125 % 10 = 5
So 361437-00-5 is a valid CAS Registry Number.

361437-00-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name [4-(4-fluorophenoxy)phenyl]boronic acid

1.2 Other means of identification

Product number -
Other names (4-(4-Fluorophenoxy)phenyl)boronic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:361437-00-5 SDS

361437-00-5Relevant articles and documents

CYCLIC MOLECULES AS BRUTON'S TYROSINE KINASE INHIBITOR

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Paragraph 0172; 0175-0176, (2021/11/26)

The present invention relates to a novel molecule with protein tyrosine kinase inhibitory activity, and the synthesis and usage thereof. Specifically, the present invention relates to compound by formula A, pharmaceutically acceptable salts, hydrates or solvates thereof, and the synthesis and usage thereof.

Pyrazolopyrimidine derivative, preparation method, pharmaceutical composition and application

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Paragraph 0339; 0340; 0341, (2017/07/19)

The invention discloses a pyrazolopyrimidine derivative, a preparation method, a pharmaceutical composition and application. The invention provides the pyrazolopyrimidine derivative as shown in a formula I and stereoisomer or solvate or pharmaceutically acceptable salts or active metabolite or prodrug thereof. The pyrazolopyrimidine derivative as shown in the formula I has good inhibitory activity on Bruton's tyrosine kinase (Btk) and particularly has good in vitro and in vivo inhibitory activity on growth of tumor cells, and a good marketization prospect is achieved. Please see the formula I in the description.

Platinum(II) cyclometallates featuring broad emission bands and their applications in color-tunable OLEDs and high color-rendering WOLEDs

Tan, Guiping,Chen, Shuming,Siu, Chi-Ho,Langlois, Adam,Qiu, Yongfu,Fan, Hongbo,Ho, Cheuk-Lam,Harvey, Pierre D.,Lo, Yih Hsing,Liu, Li,Wong, Wai-Yeung

, p. 6016 - 6026 (2016/07/06)

Two phosphorescent platinum(ii) cyclometallated complexes with phenoxy groups (1 and 2) have been developed. The modified organic ligands derived by combining the phenoxy moiety and 2-phenylpyridine conferred them with a more flexible structure, leading to superior intermolecular interaction properties of the resulting Pt(ii) metallophosphors. Because of the excimer formation induced by Pt(ii) complexes 1 and 2, the emission color can be tuned over a wide range from cyan to orange by simply increasing the concentration of the Pt(ii) metallophosphors. Inspired by their broad emission band, color tunability and outstanding electroluminescence (EL) performance, these two Pt(ii) phosphors complemented with blue fluorescent emitter 4,4′-bis(9-ethyl-3-carbazovinylene)-1,1′-biphenyl (BCzVBi) were employed in manufacturing high color-rendering white organic light-emitting devices (WOLEDs). In such simple two-emitter systems, 1-based WOLEDs exhibited reasonable EL performance with an external quantum efficiency (ηext) of 11.7%, luminance efficiency (ηL) of 29.1 cd A-1, power efficiency (ηp) of 16.9 lm W-1 and color rendering index (CRI) of 77, whereas 2-based WOLEDs demonstrated an ηext of 10%, ηL of 21.7 cd A-1, ηp of 10.7 lm W-1 and CRI of 88.

INHIBITORS OF FATTY ACID AMIDE HYDROLASE

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Page/Page column 185, (2008/12/05)

The present invention provide compounds, and pharmaceutical compositions thereof, encompassed by the formulae (I), (II) or (III). The present invention also provides methods for treating FAAH mediated disease, disorder or condition by administering a ther

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