NOVEL DIHYDROPYRIDINONE AND DIHYDROPYRIMIDINONE COMPOUNDS AND THEIR USE
The present invention is directed to novel compounds of Formula I; pharmaceutically acceptable salts or solvates thereof, and their use.
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Page/Page column 53; 54
(2017/12/27)
2-OXO-3,4-DIHYDROPYRIDINE-5-CARBOXYLATES AND THEIR USE
The present invention is directed to novel compounds of Formula (I), pharmaceutically acceptable salts or solvates thereof, and their use.
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Page/Page column 73; 116
(2016/04/20)
Mesostructured SBA-15-Pr-SO3H: An efficient solid acid catalyst for one-pot and solvent-free synthesis of 3,4-dihydro-2-pyridone derivatives
3,4-Dihydro-2-pyridone derivatives have been prepared efficiently via a one-pot four-component reaction of benzaldehyde derivatives, Meldrum's acid, methyl acetoacetate and ammonium acetate in the presence of sulphonic acid-functionalized ordered nanoporo
Enantioselective synthesis of dihydropyridinones via NHC-Catalyzed Aza-Claisen reaction
N-Heterocyclic carbene catalyzed aza-Claisen annulations of enals or their α-hydroxyenone surrogates with vinylogous amides afford dihydropyridinones. The reaction proceeds with a broad range of substrates, and no nitrogen protecting group is required.
Wanner, Benedikt,Mahatthananchai, Jessada,Bode, Jeffrey W.
supporting information; experimental part
p. 5378 - 5381
(2011/12/02)
Rapid microwave-assisted liquid-phase synthesis of 4-substituted-5- methoxycarbonyl-6-methyl-3,4-dihydropyridones on poly(ethylene glycol) support
4-Substituted-5-methoxycarbonyl-6-methyl-3,4-dihydropyridones have been efficiently prepared on the soluble polymer polyethylene glycol (PEG) 4000 by solvent-free microwave irradiation through a one-pot condensation of PEG-bound acetoacetate, Meldrum's acid, ammonium acetate, and the appropriate aldehyde in the presence of a catalytic amount of polyphosphoric acid. The polymer-supported synthesis provided the target compounds in excellent yield and purity with a facile workup procedure. Copyright Taylor & Francis Group, LLC.
Solvent-free synthesis of 4-aryl substituted 5-alkoxycarbonyl-6-methyl-3,4-dihydropyridones under microwave irradiation
4-Aryl substituted 5-alkoxycarbonyl-6-methyl-3,4-dihydropyridones have been prepared in one-pot condensation from Meldrum's acid, methyl acetoacetate and the appropriate benzaldehyde in the presence of ammonium acetate using microwave irradiation without
Rodríguez, Hortensia,Suarez, Margarita,Pérez, Rolando,Petit, Alain,Loupy, André
p. 3709 - 3712
(2007/10/03)
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