362706-25-0

Basic information

• Product Name: 1-BOC-5-Methyl-3-pyrrolidinone
• Synonyms: 1-BOC-5-Methyl-3-pyrrolidinone;2-Methyl-4-oxo-1-pyrrolidinecarboxylic acid tert-butyl ester;tert-Butyl 2-Methyl-4-oxopyrrolidine-1-carboxylate;2-methyl-4-oxo-1-Pyrrolidinecarboxylic acid 1,1-dimethylethyl ester
• CAS NO: 362706-25-0
• Molecular Formula: C10H17NO3
• Molecular Weight: 199.24688
• Mol File: 362706-25-0.mol

Chemical Properties

• Boiling Point: 280℃
• Flash Point: 123℃
• Appearance: /
• Density: 1.086
• Storage Temp.: 2-8°C
• PKA: -1.72±0.40(Predicted)
• CAS DataBase Reference: 1-BOC-5-Methyl-3-pyrrolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BOC-5-Methyl-3-pyrrolidinone(362706-25-0)
• EPA Substance Registry System: 1-BOC-5-Methyl-3-pyrrolidinone(362706-25-0)

Safety Data

• Hazardous Substances Data: 362706-25-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Chemistry:
1-BOC-5-Methyl-3-pyrrolidinone is used as a reagent for chemical synthesis, particularly in the field of organic chemistry, due to its high reactivity and versatility. It enables a broad range of reactions and processes, contributing to the development and production of various organic compounds.
Used in Pharmaceutical Industry:
1-BOC-5-Methyl-3-pyrrolidinone is used as an intermediate in the synthesis of pharmaceutical compounds for its ability to facilitate the formation of complex organic molecules, which are essential in the creation of new drugs and therapeutic agents.
Used in Research and Development:
In the research and development sector, 1-BOC-5-Methyl-3-pyrrolidinone is utilized as a key component in the exploration of new chemical reactions and the synthesis of novel organic compounds, driving innovation and advancement in the field of chemistry.
Used in Material Science:
1-BOC-5-Methyl-3-pyrrolidinone is employed in the synthesis of advanced materials, such as polymers and other specialty materials, leveraging its reactivity and versatility to create new materials with unique properties for various applications.

Upstream product

• 23770-07-2 (+,)-N-benzyl-5-methylpyrrolidin-3-one 
• 24424-99-5 di-tert-butyl dicarbonate 
• 156865-72-4 tert-butyl 4-hydroxy-2-methylpyrrolidine-1-carboxylate 
• 897046-42-3 1-[(1,1-dimethylethoxy)-carbonyl]-4-hydroxy-2-pyrrolidine carboxylic acid methyl ester 

Downstream Products

• 1584148-14-0 N-((R)-1-(3-chlorophenyl)ethyl)-5-methyl-2-((tetrahydro-2H-pyran-4-yl)amino)-5H-pyrrolo[3,4-d]pyrimidine-6(7H)-carboxamide 

Relevant articles and documents

DIHYDROPYRROLIDINO-PYRIMIDINES AS KINASE INHIBITORS

The present invention provides compounds of Formula (I) and pharmaceutically acceptable salts thereof; as further described herein. The present invention further provides pharmaceutical compositions comprising these compounds, and combinations comprising these compounds combined with or used with a therapeutic co-agent, as well as therapeutic uses of these compounds and compositions. These are useful in the treatment of diseases such as cancer that are associated with activation of ERKl and/or ERK2, and especially for MAPK pathway dependent cancers showing resistance to Raf and/or MEK inhibitory cancer therapeutics

BIS-PYRIDYLPYRIDONES AS MELANIN-CONCENTRATING HORMONE RECEPTOR 1 ANTAGONISTS

The invention provides novel bis-pyridylpyridones which are antagonists at the melanin-concentrating hormone receptor 1 (MCHR1 ), pharmaceutical compositions containing them, processes for their preparation, and their use in therapy and for the treatment of obesity and diabetes.

Beta-Amino-Acid derivatives as inhibitors of matrix metalloproteases and TNF-Alpha

The present application describes novel β-amino acid derivatives of formula I: or pharmaceutically acceptable salt or prodrug forms thereof, wherein A, X, Z, Ua, Xa, Ya, Za, R1, R2, R3, R4, and R4a are defined in the present specification, which are useful as metalloprotease and/or as TNF-α inhibitors.