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CAS

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367501-41-5

5-Methanesulfonyl-1H-indole-2-carboxylic acid, also known as MSICA, is a synthetic chemical compound derived from the indole family. It features a sulfonyl group and a carboxylic acid group, which contribute to its unique structural properties and chemical reactivity. MSICA is a promising building block in the pharmaceutical industry for the synthesis of various drugs and pharmaceutical compounds, as well as a valuable component in research and development for new drug and chemical compound discovery.

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  • 367501-41-5 Structure

  • Basic information

    1. Product Name: 5-Methanesulfonyl-1H-indole-2-carboxylic acid
    2. Synonyms: 5-Methanesulfonyl-1H-indole-2-carboxylic acid;5-(Methylsulfonyl)-1H-indole-2-carboxylic acid
    3. CAS NO:367501-41-5
    4. Molecular Formula: C10H9NO4S
    5. Molecular Weight: 239.24776
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 367501-41-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 5-Methanesulfonyl-1H-indole-2-carboxylic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5-Methanesulfonyl-1H-indole-2-carboxylic acid(367501-41-5)
    11. EPA Substance Registry System: 5-Methanesulfonyl-1H-indole-2-carboxylic acid(367501-41-5)

  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 367501-41-5(Hazardous Substances Data)

367501-41-5 Usage

Uses

Used in Pharmaceutical Industry:
5-Methanesulfonyl-1H-indole-2-carboxylic acid is used as a building block for the synthesis of various drugs and pharmaceutical compounds. Its unique structural properties and chemical reactivity make it a valuable component in the development of new medications and therapies.
Used in Research and Development:
MSICA is utilized in the research and development of new drugs and chemical compounds. Its potential therapeutic applications are being explored, and further studies and research are needed to fully understand its pharmacological and biological effects, which could lead to the discovery of novel treatments and advancements in medicine.

Check Digit Verification of cas no

The CAS Registry Mumber 367501-41-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,7,5,0 and 1 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 367501-41:
(8*3)+(7*6)+(6*7)+(5*5)+(4*0)+(3*1)+(2*4)+(1*1)=145
145 % 10 = 5
So 367501-41-5 is a valid CAS Registry Number.

367501-41-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-methylsulfonyl-1H-indole-2-carboxylic acid

1.2 Other means of identification

Product number -
Other names 5-Methanesulfonyl-1H-indole-2-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:367501-41-5 SDS

367501-41-5Relevant articles and documents

ANTIBODY-DRUG CONJUGATES COMPRISING ANTI-B7-H3 ANTIBODIES

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Page/Page column 149; 177-182, (2022/01/04)

The present disclosure relates to antibody-drug conjugates (ADCs) wherein one or more active agents are conjugated to an anti-B7-H3 antibody through a linker. The linker may comprise a unit that covalently links active agents to the antibody. The disclosure further relates to monoclonal antibodies and antigen binding fragments, variants, multimeric versions, or bispecifics thereof that specifically bind B7-H3, as well as methods of making and using these anti-B7-H3 antibodies and antigen-binding fragments thereof in a variety of therapeutic, diagnostic and prophylactic indications

Synthesis and evaluation of a series of C5′-substituted duocarmycin SA analogs

Robertson, William M.,Kastrinsky, David B.,Hwang, Inkyu,Boger, Dale L.

body text, p. 2722 - 2725 (2011/07/06)

The synthesis and evaluation of a key series of analogs of duocarmycin SA, bearing a single substituent at the C5′ position of the DNA binding subunit, are described.

Chemical compounds

-

, (2008/06/13)

The present invention provides a compound of a formula (I): wherein the variables are defined herein; to a process for preparing such a compound; and to the use of such a compound in the treatment of a chemokine (such as CCR3) or H1 mediated disease state.

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