- A process for the preparation of bisphenols
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The invention relates to a process for the preparation of bisphenols of the chemical formula wherein R represents a divalent hydrocarbon radical, which comprises in a first step reacting 2,6-di-tert.butylphenol or 2,6-di-tert.amylphenol with a dihalide Ha
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- Bisbenzoxazines and pharmaceutical use
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Compounds of the formula: STR1 wherein, R is H, alkyl, cycloalkyl, aryl, or heteroaryl; R1 is H, alkyl, cycloalkyl, aryl, heteroaryl, substituted heteroaryl, aralkyl, substituted aryl, halo, OR2, SR2, NR2, CF3, NO2, CN, COOR2, CHO, SO3 H or SO2 NH2, wherein R2 is H, methyl, ethyl or propyl; Y is STR2 Z is O, S, NH or CH2 ; X is --CH2 --, STR3 or --(CH2)n CHOH(CH2)n --; wherein R2 is H, methyl, ethyl or propyl; n is 1-10, and pharmaceutically acceptable salts thereof have antiallergy and antiinflammatory activity.
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