37460-22-3 Usage
Uses
Used in Nutritional Supplements:
H-ALA-GLY-ALA-OH is used as a nutritional supplement to support muscle building and protein synthesis. Its amino acid composition, particularly alanine, aids in the body's energy metabolism and contributes to the synthesis of proteins, which are essential for muscle growth and repair.
Used in Pharmaceutical Applications:
In the pharmaceutical industry, H-ALA-GLY-ALA-OH is used as a potential therapeutic agent for immune system regulation. The presence of glycine, which is crucial for the production of heme and nucleic acids, suggests that this peptide may play a role in modulating immune responses and supporting overall immune health.
Used in Antioxidant Formulations:
H-ALA-GLY-ALA-OH is used as an antioxidant in various formulations, capitalizing on the antioxidant properties of glycine. This tri-peptide may help protect cells from oxidative stress and support overall antioxidant defense, contributing to the maintenance of cellular health and reducing the risk of oxidative damage-related diseases.
Used in Cosmetics:
In the cosmetics industry, H-ALA-GLY-ALA-OH is used as an ingredient in skincare products for its potential benefits in promoting skin health. The peptide's amino acid composition may contribute to the maintenance of skin elasticity and hydration, as well as providing antioxidant protection to the skin, helping to reduce the signs of aging and environmental damage.
Check Digit Verification of cas no
The CAS Registry Mumber 37460-22-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,4,6 and 0 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 37460-22:
(7*3)+(6*7)+(5*4)+(4*6)+(3*0)+(2*2)+(1*2)=113
113 % 10 = 3
So 37460-22-3 is a valid CAS Registry Number.
37460-22-3Relevant articles and documents
Methyl group steric effects on the kinetics of the copper(II)-tripeptide reactions with triethylenetetramine
Schwederski, Brigitte E.,Basile-D'Alessandro, Franco,Dickson, Peter N.,Lee, Hsiupu D.,Raycheba, John M. T.,Margerum, Dale W.
, p. 3477 - 3480 (2008/10/08)
Rates of reaction of triethylenetetramine (trien) with doubly deprotonated (tripeptido)cuprate(II) complexes are measured as a function of the number and position of methyl groups in the amino acid residues. Twelve tripeptides that consist of glycyl (G), L-alanyl (A), and α-aminoisobutyryl (Aib) residues are compared. The Cu(H-2Aib3)- complex reacts 8 orders of magnitude more slowly with trien than does the Cu(H-2G3)- complex. Methyl groups on the α-carbon of the second and third amino acid residues (from the amino terminus) decrease the rate of the trien substitution reaction to a much greater extent than methyl groups on the first residue. An empirical correlation between the second-order rate constant (Ktrien, M-1 s-1 at 25.0°C, pH ? 11) and the number and position of the methyl groups is found: log ktrien = 6.7 - 0.2C1 - 2.2C2 - 1.6C3, where Ci denotes the number of methyl groups in the ith amino acid residue. The enormous changes in reactivity are attributed primarily to steric effects in these ligand-ligand exchange reactions.
