374889-30-2

Basic information

• Product Name: Benzamide, 3-amino-2-methyl- (9CI)
• Synonyms: Benzamide, 3-amino-2-methyl- (9CI);3-amino-2-methylbenzamide(SALTDATA: FREE)
• CAS NO: 374889-30-2
• Molecular Formula: C₈H₁₀N₂O
• Molecular Weight: 150.1778
• Product Categories: AMIDE;AMINEPRIMARY
• Mol File: 374889-30-2.mol

Chemical Properties

• Boiling Point: 288.163°C at 760 mmHg
• Flash Point: 128.077°C
• Appearance: /
• Density: 1.185g/cm³
• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.616
• PKA: 16.27±0.50(Predicted)
• CAS DataBase Reference: Benzamide, 3-amino-2-methyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 3-amino-2-methyl- (9CI)(374889-30-2)
• EPA Substance Registry System: Benzamide, 3-amino-2-methyl- (9CI)(374889-30-2)

Safety Data

• Hazardous Substances Data: 374889-30-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Benzamide, 3-amino-2-methyl(9CI) is used as a building block in organic synthesis for the development of new pharmaceutical compounds. Its unique structure allows for the creation of diverse drug candidates with potential therapeutic applications.
Used in Organic Synthesis:
In the field of organic synthesis, Benzamide, 3-amino-2-methyl(9CI) is utilized as a key intermediate for the synthesis of heterocyclic compounds. Its presence in these reactions contributes to the formation of complex organic molecules with specific biological activities.
Used in Antimicrobial Applications:
Benzamide, 3-amino-2-methyl(9CI) has been studied for its antimicrobial properties, making it a potential candidate for use in the development of new antimicrobial agents to combat resistant strains of bacteria.
Used in Anti-inflammatory Applications:
Benzamide, 3-amino-2-methyl(9CI) has also been investigated for its anti-inflammatory properties, suggesting its potential use in the treatment of inflammatory conditions and diseases.
Overall, Benzamide, 3-amino-2-methyl(9CI) is a multifaceted chemical compound with a broad spectrum of applications, particularly in the pharmaceutical and chemical industries, where its unique structure and properties are leveraged for the advancement of new therapeutic agents and synthetic methodologies.

InChI:InChI=1/C8H10N2O/c1-5-6(8(10)11)3-2-4-7(5)9/h2-4H,9H2,1H3,(H2,10,11)

Upstream product

• 290366-59-5 2-methyl-3-nitro-benzoic acid amide 

Downstream Products

• 374886-53-0 3-[3-(3-Methoxypropyl)-5-(6-phenylpyridin-3-yl)-4H-1,2,4-triazol-4-yl]-2-methylbenzamide 
• 1332301-97-9 3-(4-chloro-1,3,5-triazin-2-ylamino)-2-methylbenzamide 
• 1332300-67-0 3-(4-(4-(3,4-dimethylphenyl)piperazin-1-yl)-1,3,5-triazin-2-ylamino)-2-methylbenzamide 
• 1332300-23-8 3-(4-(4-hydroxypiperidin-1-yl)-1,3,5-triazin-2-ylamino)-N-methylbenzamide 
• 1332301-98-0 3-(4-(6-bromo-3,4-dihydroisoquinolin-2(1H)-yl)-1,3,5-triazin-2-ylamino)-2-methylbenzamide 
• 374889-14-2 3-[3-(biphenyl-4-yl)-5-ethyl-4H-1,2,4-triazol-4-yl]-2-methylbenzamide 
• 374889-76-6 3-[3-(biphenyl-4-yl)-5-ethyl-4H-1,2,4-triazol-4-yl]-2-methylbenzonitrile 
• 1416275-28-9 3-[3-ethyl-5-(6-phenylpyridin-3-yl)-4H-1,2,4-triazol-4-yl]-2-methylbenzamide 
• 374886-55-2 3-[3-ethyl-5-(6-phenylpyridin-3-yl)-4H-1,2,4-triazol-4-yl]-2-methylbenzonitrile 

Relevant articles and documents

Triazole derivatives

The invention relates to a triazole derivative with an activity inhibiting glycine transporter and for use as a pharmaceutical drug, and a novel triazole derivative. The inventive triazole derivative has an excellent activity inhibiting glycine transporter and is useful as a therapeutic agent of dementia, schizophrenia, cognitive disorders, or cognitive disorders involved in various diseases such as Alzheimer disease, Parkinson's disease, or Huntington disease or the like, or spasm involved in diseases such as nerve degenerative diseases and cerebrovascular disorders, or the like. Particularly, the pharmaceutical drug is useful for the amelioration of learning disability of dementia and the like.