37599-59-0

Basic information

• Product Name: 1H-pyrazol-4-ylmethylamine
• Synonyms: 1H-pyrazol-4-ylmethylamine;1-(1H-PYRAZOL-4-YL)METHANAMINE;ART-CHEM-BB B037991;VITAS-BB TBB002599;(1H-pyrazol-4-yl)methanamine;4-AMinoMethyl-1H-pyrazole;4-(AMinoMethyl)pyrazole;C-(1H-Pyrazol-4-yl)-methylamine
• CAS NO: 37599-59-0
• Molecular Formula: C₄H₇N₃
• Molecular Weight: 97.12
• Mol File: 37599-59-0.mol

Chemical Properties

• Boiling Point: 284.8±15.0 °C(Predicted)
• Appearance: /
• Density: 1.199±0.06 g/cm3(Predicted)
• PKA: 14.62±0.50(Predicted)
• CAS DataBase Reference: 1H-pyrazol-4-ylmethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-pyrazol-4-ylmethylamine(37599-59-0)
• EPA Substance Registry System: 1H-pyrazol-4-ylmethylamine(37599-59-0)

Safety Data

• Hazardous Substances Data: 37599-59-0(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
1H-pyrazol-4-ylmethylamine is used as a building block for the synthesis of more complex organic compounds. Its primary amine group allows for further chemical reactions, making it a versatile starting material in the creation of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Development:
1H-pyrazol-4-ylmethylamine is used as an intermediate in the development of new drugs. Its unique structure and reactivity can be exploited to design and synthesize novel therapeutic agents with potential applications in various medical fields.
Used in Research and Development:
1H-pyrazol-4-ylmethylamine is used as a research compound for studying the properties and reactivity of aromatic amines. It can serve as a model compound to understand the behavior of similar compounds in chemical reactions and to develop new synthetic methodologies.
Used in Material Science:
1H-pyrazol-4-ylmethylamine is used as a component in the development of new materials with specific properties. Its incorporation into polymers or other materials can lead to the creation of materials with tailored characteristics, such as improved conductivity, stability, or reactivity.

Upstream product

• 31108-57-3 1H-pyrazole-4-carbonitrile 

Downstream Products

• 1605327-06-7 (S)-N-((1H-pyrazol-4-yl)methyl)-4-((1-(5-methyl-4-oxo-3-phenyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl)amino)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide 
• 1107620-72-3 tert-butyl ((1H-pyrazol-4-yl)methyl)carbamate 

Relevant articles and documents

CANCER TREATMENTS TARGETING CANCER STEM CELLS

Disclosed are compounds, methods, compositions, and kits that allow for treating cancer by, e.g., targeting cancer stem cells. In some embodiments, the cancer is colorectal cancer, gastric cancer, gastrointestinal stromal tumor, ovarian cancer, lung cancer, breast cancer, pancreatic cancer, prostate cancer, testicular cancer, or lymphoma. In some embodiments, the cancer is liver cancer, endometrial cancer, leukemia, or multiple myeloma. The compounds utilized in the disclosure are of Formula (0), (O'), and (I):

SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF

Provided herein are small molecule activators of Nicotinamide Phosphoribosyltransferase (NAMPT), compositions comprising the compounds, and methods of using the compounds and compositions.

COMPOUNDS FOR THE MODULATION OF MYC ACTIVITY

The present invention provides novel compounds of Formula (I) and Formula (II) and pharmaceutically acceptable salts, solvates, hydrates, tautomers, stereoisomers, isotopically labeled derivatives, and compositions thereof. Also provided are methods and kits involving the compounds or compositions for treating or preventing proliferative diseases, e.g., cancers (e.g., breast cancer, prostate cancer, lymphoma, lung cancer, pancreatic cancer, ovarian cancer, neuroblastoma, or colorectal cancer), benign neoplasms, angio genesis, inflammatory diseases, fibrosis (e.g., polycystic kidney disease), autoinflammatory diseases, and autoimmune diseases in a subject.