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4-BROMO-2-METHYLBENZYLAMINE, an anilides organic compound, is characterized by its molecular formula C8H10BrN and a molecular weight of 196.079 g/mol. It is a pale yellow to brown liquid with a strong, unpleasant odor and is considered moderately hazardous, necessitating proper safety precautions during handling.

376646-62-7

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376646-62-7 Usage

Uses

Used in Pharmaceutical Industry:
4-BROMO-2-METHYLBENZYLAMINE is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of various medicinal compounds.
Used in Agrochemical Industry:
4-BROMO-2-METHYLBENZYLAMINE is utilized as an intermediate in the production of agrochemicals, playing a role in the creation of substances that aid in crop protection and enhancement.
Used as a Reagent:
In the chemical industry, 4-BROMO-2-METHYLBENZYLAMINE is used as a reagent in the preparation of various compounds, highlighting its versatility in chemical synthesis processes.

Check Digit Verification of cas no

The CAS Registry Mumber 376646-62-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,6,6,4 and 6 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 376646-62:
(8*3)+(7*7)+(6*6)+(5*6)+(4*4)+(3*6)+(2*6)+(1*2)=187
187 % 10 = 7
So 376646-62-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H10BrN/c1-6-4-8(9)3-2-7(6)5-10/h2-4H,5,10H2,1H3

376646-62-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (4-bromo-2-methylphenyl)methanamine

1.2 Other means of identification

Product number -
Other names Benzenemethanamine,4-bromo-2-methyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:376646-62-7 SDS

376646-62-7Relevant articles and documents

3-[(1H-PYRAZOL-4-YL)OXY]PYRAZIN-2-AMINE COMPOUNDS AS HPK1 INHIBITOR AND USE THEREOF

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Page/Page column 55-56; 81-82, (2022/04/09)

Disclosed herein is 3- [ (1H-pyrazol-4-yl) oxy] pyrazin-2-amine compounds of Formula (I), or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, and pharmaceutical compositions comprising thereof. Also disclosed is a method of modulating, e.g., inhibiting or treating HPK1 related disorders or diseases including cancer by using the compound disclosed herein

COMPOUNDS USEFUL IN INHIBITING DIACYLGLYCEROL O-ACYLTRANSFERASE AND METHODS OF MAKING AND USING THE SAME

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Page/Page column 25, (2021/08/20)

Described herein are compounds that may act as an inhibitor of diacylglycerol O- acyltransferase 2 (DGAT2) and/or that may be useful in the treatment of diseases and/or disorders associated with DGAT2. Compositions including such compounds are also described herein along with methods of preparation and use of such compounds and/or compositions.

Discovery of BIIB068: A Selective, Potent, Reversible Bruton's Tyrosine Kinase Inhibitor as an Orally Efficacious Agent for Autoimmune Diseases

Ma, Bin,Bohnert, Tonika,Otipoby, Kevin L.,Tien, Eric,Arefayene, Million,Bai, Judy,Bajrami, Bekim,Bame, Eris,Chan, Timothy R.,Humora, Michael,Macphee, J. Michael,Marcotte, Douglas,Mehta, Devangi,Metrick, Claire M.,Moniz, George,Polack, Evelyne,Poreci, Urjana,Prefontaine, Annick,Sheikh, Sarah,Schroeder, Patricia,Smirnakis, Karen,Zhang, Lei,Zheng, Fengmei,Hopkins, Brian T.

, p. 12526 - 12541 (2020/12/17)

Autoreactive B cell-derived antibodies form immune complexes that likely play a pathogenic role in autoimmune diseases. In systemic lupus erythematosus (SLE), these antibodies bind Fc receptors on myeloid cells and induce proinflammatory cytokine producti

INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE

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Page/Page column 40; 41, (2020/11/30)

Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.

INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE

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Page/Page column 48, (2019/12/04)

Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, methods for use as Bruton's tyrosine kinase and methods of production.

PYRAZOLOPYRIMIDINE DERIVATIVES AS BTK INHIBITORS FOR THE TREATMENT OF CANCER

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Paragraph 00224; 00509; 00510, (2017/05/02)

This invention relates to novel compounds. The compounds of the invention are tyrosine kinase inhibitors. Specifically, the compounds of the invention are useful as inhibitors of Bruton's tyrosine kinase (BTK). The invention also contemplates the use of t

ADIPATE FORMS AND COMPOSITIONS OF BIARYL INHIBITORS OF BRUTON'S TYROSINE KINASE

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Paragraph 0114, (2016/12/26)

The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.

BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY

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Paragraph 0617, (2015/06/25)

The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.

BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY

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Paragraph 0195, (2015/06/25)

The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.

SUBSTITUTED QUINOLONES

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Page/Page column 51, (2010/02/15)

The invention relates to substituted quinolones methods for production and use thereof for the production of medicaments for the treatment and/or prophylaxis of diseases, in particular, for use as antiviral agents, in particular, against cytomegaloviruses.

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