- Synthesis of polycyclic molecules by double C(sp2)-H/C(sp 3)-H arylations with a single palladium catalyst
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Polycyclic molecules were obtained in good yields by double C(sp 2)-H/C(sp3)-H arylations mediated by a single palladium/phosphine catalyst. Both double intermolecular/intramolecular and intramolecular/intramolecular C-C couplings we
- Pierre, Cathleen,Baudoin, Olivier
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supporting information; experimental part
p. 1816 - 1819
(2011/06/21)
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- METHYL SULFANYL PYRMIDMES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS
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The present invention relates to pyrimidine derivatives of Formula (Ia) and (Ib) (including tautomers, isomers, prodrugs, and pharmaceutically acceptable salts thereof). Said compounds are useful in the treatment of pain (such as neuropathic pain), inflammation, and epilepsy (by acting as anticonvulsants). Methods of medical treatment making use of said compounds, as well as additional compounds of Formula (IIa) and (IIb), are also disclosed.
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Page/Page column 78-79
(2010/12/18)
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- 1-(2,6-Dichloro-4-hydroxyphenyl)-2-phenylethanes - New biological response modifiers for the therapy of breast cancer. Synthesis and evaluation of estrogenic/antiestrogenic properties
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[meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]platinum(II) complexes (meso-1-ptll′; L,l′= Cl orL = H2O and L′ = OSO3) are highly effective towards hormone-sensitive, rodent breast cancers due to their significant estroge
- Schertl, Sabine,Hartmann, Rolf W.,Batzl-Hartmann, Christine,Schlemmer, Richard,Spru, Thilo,Bernhardt, Guenther,Gust, Ronald,Schoenenberger, Helmut
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p. 125 - 137
(2007/10/03)
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- Chemical and in vitro syntheses of brominated and chlorinated 3,4′-dihydroxybibenzyls (halogenated lunularins)
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Ten halogenated lunularins 16, 17, 26, 27, 30, 31, 36, 37, 42 and 43 as model substances for a new class of halometabolites isolated from bryophytes are prepared by chemical total syntheses according to a Wittig-protocol using halogenated aldehydes and ph
- Speicher, Andreas
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p. 162 - 168
(2007/10/03)
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- Fullerene tectonics. Part 2. Synthesis and pyrolysis of halogenated benzo[c]phenanthrenes
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Halogenated benzo[c]phenanthrenes with a halogen in the hindered fiord region are prepared by the photochemical cyclisation of appropriately substituted stilbenes. Pyrolysis gives the corresponding benzo[ghi]fluoranthrenes in moderate yields. At higher temperatures a competing rearrangement pathway to cyclopenta[cd]pyrene occurs.
- Plater, M. John
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p. 2903 - 2909
(2007/10/03)
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- Tetraisoquinoline compounds which have useful pharmaceutical utility
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Tetrahydroisoquinoline compounds of formula I STR1 and pharmaceutically acceptable salts and lipophilic ester thereof have utility as analgesics and in the treatment of psychoses, Parinson''s disease, Lesch-Nyan syndrome, attention deficit disorder or cognitive impairment or in the relief of drug dependence or tardive dyskinesia.
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