- Stille coupling involving bulky groups feasible with gold cocatalyst
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Gold shuttle: Bulky groups, which will not (or only very sluggishly) undergo Stille coupling with stannanes and inexpensive ligands, can be efficiently coupled using bimetallic catalysis. A gold cocatalyst serves as an efficient shuttle to convey the bulky group from tin to palladium by reducing the steric crowding in the transition-states (see scheme). Copyright
- Delpozo, Juan,Carrasco, Desiree,Perez-Temprano, Monica H.,Garcia-Melchor, Max,Alvarez, Rosana,Casares, Juan A.,Espinet, Pablo
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supporting information
p. 2189 - 2193
(2013/04/10)
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- Palladium-catalyzed cross-coupling reactions of organogold(i) phosphanes with allylic electrophiles
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Aryl and alkenylgold(i) phosphanes react regioselectively with allylic electrophiles such as cinnamyl and geranyl halides (bromide, chloride and acetates) under palladium catalysis in THF at 80 °C to afford the α-substitution product with moderate to high yields. When the reaction is performed with a chiral enantiopure secondary acetate, the α-substituted cross-coupling product is obtained with complete inversion of the stereochemistry.
- Pena-Lopez, Miguel,Ayan-Varela, Miguel,Sarandeses, Luis A.,Sestelo, Jose Perez
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p. 1686 - 1694
(2012/03/22)
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- Synthesis, structural characterisation and reactions of some vinylgold(I) phosphane complexes
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A series of vinylgold(I) complexes [Au(CR=CHR)L] (R = H, Me; L = PPh 3, PPh2Me, PPhMe2) were prepared from the reaction of the Grignard reagents [MgBr(CR=CHR)] (R = H, Me) with the gold(I) phosphane complexes [AuCl(L)] (L = PPh3, PPh2Me, PPhMe2) at low temperature. The complexes were characterised by various spectroscopic techniques and, in the case of [Au(CMe=CHMe)(PPh 3)], by a single-crystal X-ray structure determination. The gold-carbon bonds of these vinylgold(I) complexes are easily cleaved by acids and, in the presence of potassium permanganate, by species containing acidic protons. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.
- Mohr, Fabian,Falvello, Larry R.,Laguna, Mariano
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p. 833 - 838
(2007/10/03)
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