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Acetamide, 2-cyano-N-(2-ethoxyphenyl)- (9CI) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 380427-18-9 Structure
  • Basic information

    1. Product Name: Acetamide, 2-cyano-N-(2-ethoxyphenyl)- (9CI)
    2. Synonyms: Acetamide, 2-cyano-N-(2-ethoxyphenyl)- (9CI)
    3. CAS NO:380427-18-9
    4. Molecular Formula: C11H12N2O2
    5. Molecular Weight: 204.22518
    6. EINECS: N/A
    7. Product Categories: ETHOXY
    8. Mol File: 380427-18-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 399.9±22.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.181±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: -0.97±0.10(Predicted)
    10. CAS DataBase Reference: Acetamide, 2-cyano-N-(2-ethoxyphenyl)- (9CI)(CAS DataBase Reference)
    11. NIST Chemistry Reference: Acetamide, 2-cyano-N-(2-ethoxyphenyl)- (9CI)(380427-18-9)
    12. EPA Substance Registry System: Acetamide, 2-cyano-N-(2-ethoxyphenyl)- (9CI)(380427-18-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 380427-18-9(Hazardous Substances Data)

380427-18-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 380427-18-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,8,0,4,2 and 7 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 380427-18:
(8*3)+(7*8)+(6*0)+(5*4)+(4*2)+(3*7)+(2*1)+(1*8)=139
139 % 10 = 9
So 380427-18-9 is a valid CAS Registry Number.

380427-18-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Cyano-N-(2-ethoxyphenyl)acetamide

1.2 Other means of identification

Product number -
Other names Acetamide,2-cyano-N-(2-ethoxyphenyl)-(9CI)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:380427-18-9 SDS

380427-18-9Relevant articles and documents

Low molecular weight amidoximes that act as potent inhibitors of lysine-specific demethylase 1

Hazeldine, Stuart,Pachaiyappan, Boobalan,Steinbergs, Nora,Nowotarski, Shannon,Hanson, Allison S.,Casero, Robert A.,Woster, Patrick M.

, p. 7378 - 7391 (2012/10/29)

The recently discovered enzyme lysine-specific demethylase 1 (LSD1) plays an important role in the epigenetic control of gene expression, and aberrant gene silencing secondary to LSD1 dysregulation is thought to contribute to the development of cancer. We reported that (bis)guanidines, (bis)biguanides, and their urea- and thiourea isosteres are potent inhibitors of LSD1 and induce the re-expression of aberrantly silenced tumor suppressor genes in tumor cells in vitro. We now report a series of small molecule amidoximes that are moderate inhibitors of recombinant LSD1 but that produce dramatic changes in methylation at the histone 3 lysine 4 (H3K4) chromatin mark, a specific target of LSD1, in Calu-6 lung carcinoma cells. In addition, these analogues increase cellular levels of secreted frizzle-related protein (SFRP) 2, H-cadherin (HCAD), and the transcription factor GATA4. These compounds represent leads for an important new series of drug-like epigenetic modulators with the potential for use as antitumor agents.

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