Synthesis of 3-acetyl-4-hydroxy-1-phenylpyridin-2(1H)-one derivatives
The cyclization of aryl ketone anilides 3 with diethyl malonate to affords 4-hydroxy-6-phenyl-6H-pyrano [3,2-c]-pyridin-2,5-diones 4 in good yields. 3-Acetyl-4-hydroxy-1-phenylpyridin-2(1H)-ones 5 are obtained by ring-opening reaction of 4-hydroxy-6-pheny
Nikam,Kappe
p. 215 - 220
(2015/01/30)
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