Synthesis of 3-substituted isoindolin-1-ones by regioselective cyclization of nitrile with a styryl double bond
An efficient preparation of 3-substituted isoindolin-1-one was established via basic condensation of aromatic or aliphatic aldehyde with 6-alkoxy-3-methylbenzene-1,2,4-tricarbonitrile (1) in a one-pot reaction. The key step involved regioselective either
Luo, Fen-Tair,Chen, Chin-Hsin
p. 1663 - 1678
(2007/10/03)
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