383142-69-6

Basic information

• Product Name: 4-(4-FLUOROPHENYL)-1,3-THIAZOLE-2-CARBALDEHYDE
• Synonyms: CHEMBRDG-BB 4004889;4-(4-FLUOROPHENYL)-1,3-THIAZOLE-2-CARBALDEHYDE;4-(4-FLUORO-PHENYL)-THIAZOLE-2-CARBALDEHYDE;4-(4-fluorophenyl)-1,3-thiazole-2-carbaldehyde(SALTDATA: FREE)
• CAS NO: 383142-69-6
• Molecular Formula: C₁₀H₆FNOS
• Molecular Weight: 207.22
• Mol File: 383142-69-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(4-FLUOROPHENYL)-1,3-THIAZOLE-2-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-FLUOROPHENYL)-1,3-THIAZOLE-2-CARBALDEHYDE(383142-69-6)
• EPA Substance Registry System: 4-(4-FLUOROPHENYL)-1,3-THIAZOLE-2-CARBALDEHYDE(383142-69-6)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26
• Hazardous Substances Data: 383142-69-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-(4-Fluorophenyl)-1,3-thiazole-2-carbaldehyde is used as a key intermediate for the synthesis of various pharmaceuticals and bioactive compounds. Its unique structure and functional groups contribute to the development of new drugs with potential therapeutic applications.
Used in Organic Synthesis:
In the field of organic synthesis, 4-(4-Fluorophenyl)-1,3-thiazole-2-carbaldehyde is utilized as a building block for the creation of diverse heterocyclic compounds. Its presence in these compounds can influence their chemical properties and reactivity, making it a valuable component in the synthesis of complex organic molecules.
Used in Antimicrobial Applications:
4-(4-Fluorophenyl)-1,3-thiazole-2-carbaldehyde has been studied for its potential antifungal and antibacterial properties. It is used as a compound with antimicrobial activity, which can be further explored and optimized for use in pharmaceuticals or other applications where resistance to microbial infections is required.
Used in Research and Development:
In research and development settings, 4-(4-Fluorophenyl)-1,3-thiazole-2-carbaldehyde is employed as a subject of study to understand its chemical behavior, reactivity, and potential applications in various chemical and biological processes. This research can lead to the discovery of new uses and applications for the compound.

Downstream Products

• 918305-24-5 3-(4-(4-fluorophenyl)thiazol-2-yl)propenal 

Relevant articles and documents

Heteroaryl-substituted amides comprising an unsaturated or cyclic linker group, and their use as pharmaceuticals

The present invention relates to N-alkylamides of the formula I, in which A, Het, X, R 1 , R 2 and R 3 have the meanings indicated in the claims, which modulate the transcription of endothelial nitric oxide (NO) synthase and are valuable pharmacologically active compounds. Specifically, the compounds of the formula I upregulate the expression of the enzyme endothelial NO synthase and can be applied in conditions in which an increased expression of said enzyme or an increased NO level or the normalization of a decreased NO level is desired. The invention further relates to processes for the preparation of compounds of the formula I, to pharmaceutical compositions comprising them, and to the use of compounds of the formula I for the manufacture of a medicament for the stimulation of the expression of endothelial NO synthase or for the treatment of various diseases including cardiovascular disorders such as atherosclerosis, thrombosis, coronary artery disease, hypertension and cardiac insufficiency, for example.