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[3-METHOXY-4-(2-PROPYNYLOXY)PHENYL]METHANOL, also known as propargylphenylmethanol, is a phenolic chemical compound with the molecular formula C12H14O3. It features a methoxy group and a propynyl ether group attached to a benzene ring, which contributes to its potential applications in various industries.

385383-48-2

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385383-48-2 Usage

Uses

Used in Organic Synthesis:
[3-METHOXY-4-(2-PROPYNYLOXY)PHENYL]METHANOL is used as a building block in the synthesis of various organic compounds due to its unique structure and functional groups.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, [3-METHOXY-4-(2-PROPYNYLOXY)PHENYL]METHANOL is used as a starting material or intermediate in the development of new drugs. Its potential biological activity makes it a promising candidate for drug discovery and development.
Used in Agrochemical Industry:
[3-METHOXY-4-(2-PROPYNYLOXY)PHENYL]METHANOL is also utilized in the agrochemical industry, where it may serve as a precursor for the synthesis of compounds with pesticidal or herbicidal properties.
Safety Note:
It is important to handle [3-METHOXY-4-(2-PROPYNYLOXY)PHENYL]METHANOL with care, as it may possess hazardous properties. Proper safety measures should be taken during its use and storage to minimize potential risks.

Check Digit Verification of cas no

The CAS Registry Mumber 385383-48-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,8,5,3,8 and 3 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 385383-48:
(8*3)+(7*8)+(6*5)+(5*3)+(4*8)+(3*3)+(2*4)+(1*8)=182
182 % 10 = 2
So 385383-48-2 is a valid CAS Registry Number.

385383-48-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (3-methoxy-4-prop-2-ynoxyphenyl)methanol

1.2 Other means of identification

Product number -
Other names [3-methoxy-4-(2-propynyloxy)phenyl]methanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:385383-48-2 SDS

385383-48-2Downstream Products

385383-48-2Relevant articles and documents

Cationic cyclotriveratrylene-based glycoconjugate and its interaction with fullerene

Feng, Li-Juan,Li, Hui,Chen, Qi,Han, Bao-Hang

, p. 6985 - 6990 (2013)

Fullerenes exhibit interesting biological activities both in vitro and in vivo. However, the low solubility of fullerenes in aqueous media appears to be a major problem for their biological application. To exploit water-soluble macrocyclic host systems to improve the water-solubility of fullerene, a cationic water-soluble CTV derivative containing glucosamine hydrochloride (CTV-GH) is synthesized and well characterized. The supramolecular complexation between CTV-GH and C60 was investigated in organic solvent and aqueous solution, respectively, and confirmed by fluorescence, UV-vis, and Raman spectra. The CTV derivative exhibits a distinct photoluminescence, which can be used to conveniently detect its interaction with C60 through spectrofluorometric titration. CTV-GH can bind C60 in toluene-DMSO solution with the association constant Ka = 4.36 × 10 5 M-1 calculated on the hypothesis of forming a supramolecular complex with 1:1 molar ratio at 298 K. In an aqueous solution, C60 has no absorption intensity due to its insolubility. However, in the presence of CTV-GH, a new characteristic peak of C60 at 342 nm in the UV-vis absorption spectrum was observed for the C60-CTV-GH complex and its intensity greatly increases over 24 h, which proves that CTV-GH can bind C60 in aqueous solution to form a water-soluble complex. The host-guest interaction between sugar-bearing CTV and C60 in aqueous solution will boost the potential biological applications of C60.

Scaffold optimization in discontinuous epitope containing protein mimics of gp120 using smart libraries

Mulder, Gwenn E.,Quarles Van Ufford,Van Ameijde, Jeroen,Brouwer, Arwin J.,Kruijtzer, John A. W.,Liskamp, Rob M. J.

, p. 2676 - 2684 (2013)

A diversity of protein surface discontinuous epitope mimics is now rapidly and efficiently accessible. Despite the important role of protein-protein interactions involving discontinuous epitopes in a wide range of diseases, mimicry of discontinuous epitopes using peptide-based molecules remains a major challenge. Using copper(i) catalyzed azide-alkyne cycloaddition (CuAAC), we have developed a general and efficient method for the synthesis of collections of discontinuous epitope mimics. Up to three different cyclic peptides, representing discontinuous epitopes in HIV-gp120, were conjugated to a selection of scaffold molecules. Variation of the scaffold molecule, optimization of the ring size of the cyclic peptides and screening of the resulting libraries for successful protein mimics led to an HIV gp120 mimic with an IC50 value of 1.7 μM. The approach described here provides rapid and highly reproducible access to clean, smart libraries of very complex bio-molecular constructs representing protein mimics for use as synthetic vaccines and beyond.

APOPTOSIS INHIBITORS

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Paragraph 0381, (2018/02/27)

The invention provides compounds that are inhibitors or covalent modifiers of succinate dehydrogenase subunit B (SDHB) and/or inhibitors of apoptosis, and pharmaceutically acceptable salts, hydrides and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition.

Total syntheses of three copper (II) tetracarboranylphenylporphyrins containing 40 or 80 boron atoms and their biological properties in EMT-6 tumor-bearing mice

Wu, Haitao,Micca, Peggy L.,Makar, Michael S.,Miura, Michiko

, p. 5083 - 5092 (2008/02/05)

Three carboranyltetraphenylporphyrins containing 40 or 80 boron atoms were synthesized and evaluated for their biodistribution and toxicity in EMT-6 tumor-bearing mice. Copper (II) meso-5,10,15,20-tetrakis[3-methoxy-4-(o-carboranylmethoxy)phenyl]porphyrin

CARBORANYLPORPHYRINS AND USES THEREOF

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Page/Page column 8-9, (2008/06/13)

The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity carborane-containing 5, 10, 15,

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