Synthesis of (S)-(-)-N-acetylcolchinol using intramolecular biaryl oxidative coupling
An asymmetric synthesis of the tubulin polymerisation inhibitor (S)-(-)-N-acetylcolchinol is reported based on an intramolecular biaryl oxidative coupling of a 1,3-diarylpropyl acetamide intermediate using phenyliodonium bis(trifluoroacetate) as the final
Besong, Gilbert,Jarowicki, Krzysztof,Kocienski, Philip J.,Sliwinski, Eric,Boyle, F. Thomas
p. 2193 - 2207
(2008/02/09)
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