Carboxylation of Phenols with CO2 at Atmospheric Pressure
A convenient and efficient method for the ortho-carboxylation of phenols under atmospheric CO2 pressure has been developed. This method provides an alternative to the previously reported Kolbe-Schmitt method, which requires very high pressures of CO2. The addition of a trisubstituted phenol has proved essential for the successful carboxylation of phenols with CO2 at standard atmospheric pressure, allowing the efficient preparation of a broad variety of salicylic acids.
Luo, Junfei,Preciado, Sara,Xie, Pan,Larrosa, Igor
supporting information
p. 6798 - 6802
(2016/05/11)
AMIDE RESORCINOL COMPOUNDS
The present invention is directed to compounds of formula (I), and pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as HSP-90 inhibitors.
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(2008/06/13)
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