AMINOPYRAZOLE COMPOUNDS AND USE AS CHK1 INHIBITORS
Described herein are aminopyrazole compounds of formula (I), wherein R1, R2, L and Ar are as defined in the specification. Such compounds are capable of modulating the activity of a checkpoint kinase and methods for utilizing such mo
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Page/Page column 42; 80
(2010/02/10)
FUNCTIONALIZED ENAMINES IN THE SYNTHESIS OF SOME HETEROCYCLIC COMPOUNDS
Esters of 3-amino-2-cyanoacrylate and analogous compounds were used as starting material for pyridines which were obtained via the corresponding amidines.On the other hand, from ethyl 5-aminoisoxazole-4-carboxylate or 5-amino-4-cyanoisoxazole in a similar reaction sequence a pyrimidine derivative could be prepared.
1H AND 13C NMR STUDY OF PYRIDYLAMIDES AND THIONAMIDES
1H and 13C NMR spectra are reported for several pyridylamides and thionamides.Complete analyses of the 13C spectra have yielded the chemical shifts and the direct and long range (13C, 1H) coupling constants. 13C chemical shifts show linear relationship with charge densities computed by CNDO method.The variations in the chemical shifts are discussed.
Sudha, L. V.,Manogaran, S.,Sathyanarayana, D. N.
p. 137 - 144
(2007/10/02)
THIATION REACTIONS. PART I. REACTION OF 2,4-BIS(4-METHOXYPHENYL) -1,3,2,4-DITHIADIPHOSPHITANE-2,4-DISULFIDE WITH DIACETAMIDES AND ACETAMIDE DERIVATIVES
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Shabana, Rashad,El-Kateb, Ahmed A.
p. 647 - 650
(2007/10/02)
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