Synthesis of 3,3-and 4,4-alkyl-phenyl-substituted pyrrolidin-2-one derivatives
Syntheses of 3,3-and 4,4-alkyl-phenyl-substituted pyrrolidin-2-one derivatives are described. The final compounds were obtained by the reductive cyclization of relevant cyanoalkanoate esters using NaBH4 and CoCl2.6H2O. The obtained pyrroIidin-2-one derivatives are pharmacophoric fragments for the synthesis of various biologically active compounds.
Kulig,Ignasik,Malawska
experimental part
p. 1629 - 1636
(2010/07/06)
Synthesis of the enantiomers of some disubstituted succinic imides
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Knabe,Koch
p. 757 - 765
(2007/10/07)
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