Cyclic phosphinamides and phosphonamides, novel series of potent matrix metalloproteinase inhibitors with antitumour activity
The design, synthesis, and structure-activity relationship (SAR) of a series of novel nonpeptidic cyclic phosphon- and phosphinamide-based hydroxamic acids as inhibitors of matrix metalloproteinases MMP-1, MMP-3, and MMP-9 are presented. Based on modellin
Sorensen, Morten Dahl,Blaehr, Lars K. A.,Christensen, Mette K.,Hoyer, Thomas,Latini, Scilla,Hjarnaa, Pernille-Julia V.,Bjoerkling, Fredrik
p. 5461 - 5484
(2007/10/03)
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