39191-13-4

Basic information

• Product Name: N-PROPYLCYCLOHEPTANAMINE
• Synonyms: N-PROPYLCYCLOHEPTANAMINE;N-propylcycloheptanamine(SALTDATA: HCl)
• CAS NO: 39191-13-4
• Molecular Formula: C10H21N
• Molecular Weight: 155.28
• Mol File: 39191-13-4.mol

Chemical Properties

• Boiling Point: 209.5°C at 760 mmHg
• Flash Point: 72.1°C
• Appearance: /
• Density: 0.84g/cm³
• Vapor Pressure: 0.203mmHg at 25°C
• Refractive Index: 1.456
• CAS DataBase Reference: N-PROPYLCYCLOHEPTANAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-PROPYLCYCLOHEPTANAMINE(39191-13-4)
• EPA Substance Registry System: N-PROPYLCYCLOHEPTANAMINE(39191-13-4)

Safety Data

• Hazardous Substances Data: 39191-13-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
N-PROPYLCYCLOHEPTANAMINE is used as an intermediate in the synthesis of pharmaceuticals for its ability to participate in different types of chemical reactions, contributing to the development of new drugs and medications.
Used in Chemical Industry:
N-PROPYLCYCLOHEPTANAMINE serves as a building block in the production of various chemicals and materials, leveraging its versatile nature to create a wide range of products.
Used in Industrial Applications:
In the industrial sector, N-PROPYLCYCLOHEPTANAMINE is utilized for its potential in different types of chemical reactions, playing a crucial role in the manufacturing process of various products and materials.

InChI:InChI=1/C10H21N/c1-2-9-11-10-7-5-3-4-6-8-10/h10-11H,2-9H2,1H3

Upstream product

• 502-42-1 cycloheptanone 
• 22668-90-2 N-n-propyl-cycloheptylideneamine 
• 107-10-8 propylamine 

Downstream Products

• 1186211-98-2 4-[(3-chlorophenylsulfonamido)methyl]-N-cycloheptyl-N-propylbenzamide 

Relevant articles and documents

Sodium borohydride on wet clay: Solvent-free reductive amination of carbonyl compounds using microwaves

A solvent-flee reductive amination of carbonyl compounds by wet montmorillonite K 10 clay supported sodium borohydride is described; microwave irradiation facilitates the procedure.

Reductive amination of aldehydes and ketones with sodium triacetoxyborohydride. Studies on direct and indirect reductive amination procedures

Sodium triacetoxyborohydride is presented as a general reducing agent for the reductive amination of aldehydes and ketones. Procedures for using this mild and selective reagent have been developed for a wide variety of substrates. The scope of the reaction includes aliphatic acyclic and cyclic ketones, aliphatic and aromatic aldehydes, and primary and secondary amines including a variety of weakly basic and nonbasic amines. Limitations include reactions with aromatic and unsaturated ketones and some sterically hindered ketones and amines. 1,2-Dichloroethane (DCE) is the preferred reaction solvent, but reactions can also be carried out in tetrahydrofuran (THF) and occasionally in acetonitrile. Acetic acid may be used as catalyst with ketone reactions, but it is generally not needed with aldehydes. The procedure is carried out effectively in the presence of acid sensitive functional groups such as acetals and ketals; it can also be carried out in the presence of reducible functional groups such as C-C multiple bonds and cyano and nitro groups. Reactions are generally faster in DCE than in THF, and in both solvents, reactions are faster in the presence of AcOH. In comparison with other reductive amination procedures such as NaBH3CN/MeOH, borane-pyridine, and catalytic hydrogenation, NaBH(OAc)3 gave consistently higher yields and fewer side products. In the reductive amination of some aldehydes with primary amines where dialkylation is a problem we adopted a stepwise procedure involving imine formation in MeOH followed by reduction with NaBH4.