Peptide Synthesis in Alcohol Solvents by the Mixed Anhydride Method Using Dimethylphosphinothioyl Chloride
The formation and coupling of the dimethylphosphinothioic mixed anhydrides of protected amino acids can be performed in alcohol solvents.Sparingly soluble protected C-terminal segments of vasoactive intestinal peptide (VIP) up to the heptapeptide stage we