BIARYL NITROGEN-HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION
The present invention relates to a chemical genus of biaryl nitrogen-attached heterocycles that are inhibitors of LTA4H (leukotriene A4 hydrolase). The compounds have the general formula They are useful for the treatment and prevention and prophylaxis of
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Page/Page column 7; 8-9
(2008/06/13)
Clay catalyzed chemoselective Michael type addition of aliphatic amines to α,β-ethylenic compounds
Application of acidic clays as heterogeneous catalysts for the Michael type addition reaction of aliphatic amines to α,β-ethylenic compounds is presented. Aromatic amines do not participate in this transformation.
Shaikh, Nadim S.,Deshpande, Vishnu H.,Bedekar, Ashutosh V.
p. 9045 - 9048
(2007/10/03)
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