Piperidine derivatives and drugs containing these derivatives as active ingredient
Piperidine derivatives represented by formula (I) or nontoxic salts thereof (wherein symbols are defined in the description): Since the compound represented by formula (I) has a PDE4 inhibitory activity, it is useful for preventing and/or treating inflamm
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(2008/06/13)
Design, synthesis, and biological evaluation of new phosphodiesterase type 4 inhibitors
The mode of interaction with enzyme is hypothesized based on the SAR data. The design, synthesis, and biological evaluation of new phosphodiesterase type 4 inhibitors, which possess new templates instead of a cyclohexane ring, are described. The mode of i