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CAS

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401560-72-3

2-AMINO-3,6,7-TRIMETHYLIMIDAZO(4,5-B)PYRIDINE, also known as 7H-dibenzo[c,g]carbazole, is a heterocyclic aromatic amine that is formed during the cooking process of meats and fish at high temperatures and is also found in tobacco smoke. It is a potent carcinogen and mutagen that has been linked to DNA damage and has been shown to induce tumors in experimental animal studies.

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  • 401560-72-3 Structure

  • Basic information

    1. Product Name: 2-AMINO-3,6,7-TRIMETHYLIMIDAZO(4,5-B)PYRIDINE
    2. Synonyms: 2-AMINO-3,6,7-TRIMETHYLIMIDAZO(4,5-B)PYRIDINE;3,6,7-TriMethyl-3H-iMidazo[4,5-b]pyridin-2-aMine
    3. CAS NO:401560-72-3
    4. Molecular Formula: C9H12 N4
    5. Molecular Weight: 176.22
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 401560-72-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-AMINO-3,6,7-TRIMETHYLIMIDAZO(4,5-B)PYRIDINE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-AMINO-3,6,7-TRIMETHYLIMIDAZO(4,5-B)PYRIDINE(401560-72-3)
    11. EPA Substance Registry System: 2-AMINO-3,6,7-TRIMETHYLIMIDAZO(4,5-B)PYRIDINE(401560-72-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 401560-72-3(Hazardous Substances Data)

401560-72-3 Usage

Uses

Used in Research:
2-AMINO-3,6,7-TRIMETHYLIMIDAZO(4,5-B)PYRIDINE is used as a research chemical for studying the effects of dietary and environmental factors on cancer development. Its carcinogenic properties make it a valuable tool for understanding the mechanisms of cancer induction and progression.
Used in Toxicology Studies:
2-AMINO-3,6,7-TRIMETHYLIMIDAZO(4,5-B)PYRIDINE is used in toxicology studies to investigate the potential health risks associated with exposure to this chemical compound. These studies help to determine safe exposure levels and inform regulations and guidelines for its use in various industries.
Used in Food Safety Assessments:
2-AMINO-3,6,7-TRIMETHYLIMIDAZO(4,5-B)PYRIDINE is used in food safety assessments to evaluate the potential presence of this carcinogen in cooked meats and fish. This helps to ensure that food products are safe for consumption and meet regulatory standards for chemical contaminants.

Check Digit Verification of cas no

The CAS Registry Mumber 401560-72-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,1,5,6 and 0 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 401560-72:
(8*4)+(7*0)+(6*1)+(5*5)+(4*6)+(3*0)+(2*7)+(1*2)=103
103 % 10 = 3
So 401560-72-3 is a valid CAS Registry Number.

401560-72-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,6,7-trimethylimidazo[4,5-b]pyridin-2-amine

1.2 Other means of identification

Product number -
Other names 3,6,7-Trimethyl-3H-imidazo[4,5-b]pyridin-2-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:401560-72-3 SDS

401560-72-3Downstream Products

401560-72-3Relevant articles and documents

Synthesis of two potential heterocyclic amine food mutagens

Tanga, Mary J.,Kozocas, Joseph A.,Tochimoto, Todd K.

, p. 661 - 665 (2008/09/21)

(Chemical Equation Presented) The syntheses of two potential food mutagens formed during cooking, 2-amino-3,6,7-trimethyl-3H-imidazo[4,5-b]pyridine (1) and 2-amino-3,6,7-trimethyl-3H-imidazo[4,5-c]pyridine (2), are described.

A QSAR for the mutagenic potencies of twelve 2-amino- trimethylimidazopyridine isomers: Structural, quantum chemical, and hydropathic factors

Knize, Mark G.,Hatch,Tanga,Lau,Colvin

, p. 132 - 146 (2008/03/12)

An isomeric series of heterocyclic amines related to one found in heated muscle meats was investigated for properties that predict their measured mutagenic potency. Eleven of the 12 possible 2-amino-trimethylimidazopyridine (TMIP) isomers were tested for

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