402508-84-3Relevant articles and documents
Synthesis and evaluation of potent and selective β3 adrenergic receptor agonists containing acylsulfonamide, sulfonylsulfonamide, and sulfonylurea carboxylic acid isosteres
Uehling, David E.,Donaldson, Kelly H.,Deaton, David N.,Hyman, Clifton E.,Sugg, Elizabeth E.,Barrett, David G.,Hughes, Robert G.,Reitter, Barbara,Adkison, Kim K.,Lancaster, Mary E.,Lee, Frank,Hart, Robert,Paulik, Mark A.,Sherman, Bryan W.,True, Timothy,Cowan, Conrad
, p. 567 - 583 (2007/10/03)
Starting from phenethanolamine aniline leads 3a and 3b, we have identified a series of functionally potent and selective β3 adrenergic receptor (AR) agonists containing acylsulfonamide, sulfonylsulfonamide, or sulfonylurea groups within the ani