402924-76-9 Usage
Uses
Used in Pharmaceutical Synthesis:
[1-(2-AMINOPHENYL)PIPERIDIN-4-YL]METHANOL is used as a chemical intermediate for the synthesis of various pharmaceuticals and organic compounds. Its unique structure allows it to be a building block for the preparation of diverse biologically active molecules, contributing to the development of new drugs and therapies.
Used in Drug Discovery and Research:
In the field of drug discovery and research, [1-(2-AMINOPHENYL)PIPERIDIN-4-YL]METHANOL is used as a valuable component due to its potential medical applications. Its structural and chemical properties make it a promising candidate for the development of new drugs and therapeutic agents, targeting a wide range of medical conditions and diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 402924-76-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,2,9,2 and 4 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 402924-76:
(8*4)+(7*0)+(6*2)+(5*9)+(4*2)+(3*4)+(2*7)+(1*6)=129
129 % 10 = 9
So 402924-76-9 is a valid CAS Registry Number.
402924-76-9Relevant articles and documents
Potent 2′-aminoanilide inhibitors of cFMS as potential anti-inflammatory agents
Patch, Raymond J.,Brandt, Benjamin M.,Asgari, Davoud,Baindur, Nand,Chadha, Naresh K.,Georgiadis, Taxiarchis,Cheung, Wing S.,Petrounia, Ioanna P.,Donatelli, Robert R.,Chaikin, Margery A.,Player, Mark R.
, p. 6070 - 6074 (2008/03/18)
A series of 2′-aminoanilides have been identified which exhibit potent and selective inhibitory activity against the cFMS tyrosine kinase. Initial SAR studies within this series are described which examine aroyl and amino group substitutions, as well as the introduction of hydrophilic substituents on the benzene core. Compound 47 inhibits the isolated enzyme (IC50 = 0.027 μM) and blocks CSF-1-induced proliferation of bone marrow-derived macrophages (IC50 = 0.11 μM) and as such, serves as a lead candidate for further optimization studies.
