405198-51-8

Basic information

• Product Name: 2-(Methylthio)thiazolo[5,4-c]pyridine
• Synonyms: 2-(Methylthio)thiazolo[5,4-c]pyridine;2-methylsulfanyl-[1,3]thiazolo[5,4-c]pyridine
• CAS NO: 405198-51-8
• Molecular Formula: C₇H₆N₂S₂
• Molecular Weight: 182.26594
• Mol File: 405198-51-8.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(Methylthio)thiazolo[5,4-c]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Methylthio)thiazolo[5,4-c]pyridine(405198-51-8)
• EPA Substance Registry System: 2-(Methylthio)thiazolo[5,4-c]pyridine(405198-51-8)

Safety Data

• Hazardous Substances Data: 405198-51-8(Hazardous Substances Data)

Usage

Thiazole compounds

It belongs to the class of thiazole compounds This means that 2-(Methylthio)thiazolo[5,4-c]pyridine contains a thiazole ring, which is a five-membered ring with one sulfur and one nitrogen atom.

Thiazole ring fused with a pyridine ring

It contains a thiazole ring fused with a pyridine ring This describes the structure of the compound, in which a thiazole ring is fused to a pyridine ring, which is a six-membered ring with one nitrogen atom.

Used in various industries

It is used in industries such as pharmaceuticals and agrochemicals This indicates that the compound has potential therapeutic and pesticidal properties and is used in the development of drugs and pesticides.

Building block in the synthesis of other organic compounds

It can be used as a building block in the synthesis of other organic compounds This means that 2-(Methylthio)thiazolo[5,4-c]pyridine can be used as a starting material to create other organic compounds with different properties and applications.

Unique molecular structure and properties

Its unique molecular structure and properties make it a valuable and versatile chemical for a range of applications This highlights the importance of the compound's structure and its potential for use in various fields.

Upstream product

• 57135-09-8 1H,2H-[1,3]thiazolo[5,4-b]pyridine-2-thione 
• 74-88-4 methyl iodide 
• 2247-88-3 3-fluoro-pyridin-4-ylamine 

Downstream Products

• 305801-58-5 5-methyl-2-methylthiothiazolo[5,4-c]pyridinium tosylate 

Relevant articles and documents

General Entry into o-,o′-Heteroatom-Linked N-(Hetero)aryl-Imidazole Motifs by Gold-Catalysed Formal [3+2]-Dipolar Cycloaddition

A general redox-neutral approach into the o-,o′-heteroatom-linked N-(hetero)aryl-imidazole family of heteroaromatics has been developed. New types of heteroatom substituted carbimidoyl nitrenoids are efficiently realised from robust, bench-stable N-(heteroaryl)-pyridinium-N-aminides by formal gold-catalysed [3+2]-dipolar cycloadditions across ynamides. Broad structural variety and functional group tolerance allows rapid access into diverse functionalised scaffolds, as exemplified by the preparation of 8 different heteroaromatic cores. (Figure presented.).

Non-imidazole histamine H3 ligands. Part III. New 4-n-propylpiperazines as non-imidazole histamine H3-antagonists

In search for a new lead of non-imidazole histamine H3-receptor antagonists, a series of 1[(2-thiazolopyridine)-4-n-propyl]piperazines, the analogous 1-[(2-oxazolopyridine)-4-npropyl]piperazines, 1-[(2-benzothiazole)-4- n-propyl]piperazine and 1-[(2-benzooxazole)4-n-propyl]piperazine were prepared and in vitro tested as H3-receptor antagonists (the electrically evoked contraction of the guinea-pig jejunum). It appeared that by comparison of homologous pairs the thiazolo derivatives have slightly higher activity than their oxazolo analogues. The most potent compound of these series is the 1-(2-thiazolo[4,5-c]pyridine)-4-n-propylpiperazine (3c) with pA2 = 7.25 (its oxazole analogue (4g) showed pA2 = 6.9). The structure-activity relationships for compounds with various positions of the nitrogen in the benzene ring for the thiazoles compared with oxazoles are discussed.