- Preparation method of ticarcillin sodium key intermediate, namely 2-(3-thienyl) malonic acid
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The invention discloses a preparation method of a ticarcillin sodium key intermediate, namely 2-(3-thienyl) malonic acid, and belongs to the technical field of synthesis of ticarcillin sodium key intermediates. The key points of the technical scheme adopted by the invention are the reaction equation is as shown in the description. The preparation method provided by the invention has the outstanding characteristics that no high temperature exists in reaction conditions, the production danger is greatly reduced, the product yield is higher, and the production steps are simple to operate.
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Paragraph 0019; 0020; 0023; 0024; 0027; 0028
(2018/04/03)
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