406212-51-9

Basic information

• Product Name: Methyl N-Boc-4-hydroxypiperidine-3-carboxylate
• Synonyms: Methyl N-Boc-4-hydroxypiperidine-3-carboxylate;1-tert-Butyl 3-Methyl 4-hydroxy-1,3-piperidinedicarboxylate;1,3-Piperidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-diMethylethyl) 3-Methyl ester;1-tert-butyl 3-Methyl 4-hydroxypiperidine-1,3-dicarboxylate;4-Hydroxy-1,3-piperidinedicarboxylic acid 1-(1,1-dimethylethyl) 3-methyl ester;Methyl N-(tert-Butoxycarbonyl)-4-hydroxypiperidine-3-carboxylate
• CAS NO: 406212-51-9
• Molecular Formula: C12H21NO5
• Molecular Weight: 259.29884
• Mol File: 406212-51-9.mol

Chemical Properties

• Boiling Point: 352.1±42.0 °C(Predicted)
• Appearance: /
• Density: 1.182±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 14.12±0.40(Predicted)
• CAS DataBase Reference: Methyl N-Boc-4-hydroxypiperidine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl N-Boc-4-hydroxypiperidine-3-carboxylate(406212-51-9)
• EPA Substance Registry System: Methyl N-Boc-4-hydroxypiperidine-3-carboxylate(406212-51-9)

Safety Data

• Hazardous Substances Data: 406212-51-9(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Methyl N-Boc-4-hydroxypiperidine-3-carboxylate is used as a building block for the synthesis of various biologically active molecules and pharmaceuticals. Its unique structure allows for the creation of a wide range of compounds with potential applications in different fields.
Used in Pharmaceutical Research:
In the pharmaceutical industry, Methyl N-Boc-4-hydroxypiperidine-3-carboxylate is used as a reagent in the synthesis of diverse N-Boc-4-hydroxypiperidine-3-carboxylic acid derivatives. These derivatives have potential applications in drug discovery and development, making this compound a valuable chemical intermediate for the creation of new therapeutic agents.
Used in Drug Discovery and Development:
Methyl N-Boc-4-hydroxypiperidine-3-carboxylate is utilized in the development of new drugs, particularly those targeting specific biological pathways or diseases. Its versatility and reactivity make it an essential component in the design and synthesis of novel pharmaceutical compounds.

Upstream product

• 161491-24-3 methyl 1-tert-butoxycarbonyl-4-oxo-3-piperidinecarboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 959958-24-8 methyl 4-hydroxypiperidine-3-carboxylate 

Relevant articles and documents

SUBSTITUTED PYRIDOPYRAZINES AS NOVEL SYK INHIBITORS

Provided are pyridopyrazine compounds of formula (1), pharmaceutical compositions thereof and methods of use therefore, wherein R1, R2, R3, R4 and m are as defined in the specification.

SUBSTITUTED PYRIDOPYRAZINES AS NOVEL SYK INHIBITORS

Provided are certain pyridopyrazine compounds, pharmaceutical compositions thereof and methods of use therefor.

Pyridine derivatives

Pyridine compounds of general formula: wherein —R1represents in which R11is hydrogen, C1-6alkyl, halogen, hydroxy, C1-12alkoxy, nitro, amino, C1-6alkylsulfonylamino, C1-6alkoxycarbonyl, C1-6alkylamino, di(C1-6alkyl)amino, C1-6alkanoylamino, phenyl C1-6alkylamino, phenylsulfonylamino, or —O—(CH2)n—R111; R2represents hydrogen or halogen; R3represents hydrogen, —CR31R32R33, or —NR34R35; R4is hydrogen, carbamoyl, CN, carboxyl, etc.; R5is amino, C1-6alkylamino, di C1-6alkylamino, etc. or salt thereof. The compound has an excellent anti-inflammatory activity, and other biological activity.