Antihypertensive Thiadiazoles. 1. Synthesis of Some 2-Aryl-5-hydrazino-1,3,4-thiadiazoles with Vasodilator Activity
Some 2-Aryl-5-hydrazino-1,3,4-thiadiazoles have been synthesized and screened for antihypertensive activity.In general, compounds with a 2-substituted phenyl ring had higher activity than their 3- or 4-substituted counterparts or those containing heteroar
Turner, Stephen,Myers, Malcolm,Gadie, Brian,Nelson, Anthony J.,Pape, Robin,et al.
p. 902 - 906
(2007/10/02)
Algicidol 2-chloro-5-tolyl-1,3,4-thiadiazoles
5-Aryl-tetrazoles may be reacted with thiophosgene to yield 2-chloro-5-aryl-1,3,4-thiadiazoles which have unusually selective phytotoxic properties, being particularly useful in combating crabgrass and algae.
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(2008/06/13)
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