Concise Entries to 4-Halo-2-pyridones and 3-Bromo-4-halo-2-pyridones
Methods for the synthesis of both simple 4-halo-2-pyridones and more functionalized 3,4-di- and (3,4,5-tri)-halo-2-pyridones are described that are based on a combination of Sandmeyer and regioselective (copper-mediated) halogenation, with a 2-chloro or a 2-benzyloxy moiety serving as a masked 2-pyridone.
Honraedt, Aurélien,Gallagher, Timothy
supporting information
p. 67 - 69
(2015/12/26)
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