Trifluoroethanol as a Unique Additive for the Chemoselective Electrooxidation of Enamines to Access Unsymmetrically Substituted NH-Pyrroles
An electrochemical method for the synthesis of unsymmetrically substituted NH-pyrroles is described. The synthetic strategy comprises a challenging heterocoupling between two structurally diverse enamines via sequential chemoselective oxidation, addition,
Baidya, Mrinmay,De Sarkar, Suman,Maiti, Debabrata,Roy, Lisa
supporting information
(2021/12/23)
Reactivity of a new alkenyl phenyliodonium tosylate derived from methyl 3-aminocrotonate
Methyl 3-aminocrotonate reacts with [hydroxy(tosyloxy)iodo]benzene to afford the corresponding E-2-phenyliodonio tosylate in good yield. This new alkenyl iodonium sat upon reaction with various nucleophiles offers an easy access to substituted enamine der