- Synthesis method of 2-aminopropanol
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The invention discloses a synthesis method of 2-aminopropanol. According to the method, epoxypropane and liquid ammonia are taken as raw materials, epoxypropane and liquid ammonia are introduced intoa fixed bed reactor, the molar ratio of epoxypropane to liquid ammonia is 1: (5-20), and under the action of a rare earth modified catalyst, reaction is carried out for 10-60s at the temperature of 100-200 DEG C, so that 2-aminopropanol is obtained. The method is reasonable in process, simple and convenient to operate, high in atom economy and low in emission of three wastes, and meets the requirements of industrial production.
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Paragraph 0047-0048; 0050-0051
(2020/04/29)
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- Substituted N, N-disubstituted diamino compounds useful for inhibiting cholesteryl ester transfer protein activity
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The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating atherosclerosis and other coronary artery diseases. Preferred tertiary-heteroalkylamine compounds are substituted N,N-disubstituted diamines. A preferred specific N,N-disubstituted diamine is the compound:
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- Kinetic study of the reaction between iodide and N-chloramines
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We carried out a kinetic study of the reaction between iodide ion and various primary N-chloramines and found it to be first-order in the latter.Experiments also showed the rate constant for the reaction to be directly proportional to the iodide and hydrogen ion concentrations.The influence of the concentration reveals the presence of general acid catalysis processes.
- Antelo, J. M.,Arce, F.,Campos, J.,Parajo, M.
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p. 391 - 396
(2007/10/03)
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