41137-86-4

Basic information

• Product Name: Hirsutal
• Synonyms: Hirsutal
• CAS NO: 41137-86-4
• Molecular Formula: C₁₉H₂₂O₆
• Molecular Weight: 346.37438
• Mol File: 41137-86-4.mol

Chemical Properties

• Boiling Point: 679.6±55.0 °C(Predicted)
• Appearance: /
• Density: 1.362±0.06 g/cm3(Predicted)
• PKA: 9.76±0.10(Predicted)
• CAS DataBase Reference: Hirsutal(CAS DataBase Reference)
• NIST Chemistry Reference: Hirsutal(41137-86-4)
• EPA Substance Registry System: Hirsutal(41137-86-4)

Safety Data

• Hazardous Substances Data: 41137-86-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Hirsutal is used as a potential cancer drug for its cytotoxic properties, which have been observed to inhibit the growth of cancer cells in laboratory studies.
Used in Antifungal Applications:
Hirsutal is used as an antifungal agent due to its demonstrated effectiveness against various pathogenic fungi, offering a potential solution for treating fungal infections.
Research on Hirsutal is ongoing, and its applications may expand as further studies reveal its full therapeutic potential.

Upstream product

• 55303-93-0 oregonin 
• 1198403-80-3 oregonoyl A 

Downstream Products

• 93915-35-6 Acetic acid (S)-5-(3,4-dimethoxy-phenyl)-1-[2-(3,4-dimethoxy-phenyl)-ethyl]-3-oxo-pentyl ester 
• 55094-75-2 (S)-1,7-bis(3,4-dimethoxyphenyl)-5-hydroxy-3-heptanone 

Relevant articles and documents

Anti-influenza diarylheptanoids from the bark of Alnus japonica

This study to investigate anti-influenza components from the bark of Alnus japonica resulted in the isolation of two rare acylated diarylheptanoids, named oregonoyl A (5) and oregonoyl B (6), along with nine known compounds (1-4 and 7-11). Their structures were elucidated on the basis of extensive spectroscopic and chemical methods. Antiviral testing of compounds 1-11 against KBNP-0028 (H9N2) avian influenza virus showed that platyphyllone (10) was strongly active, and platyphyllonol-5-xylopyranoside (9) was moderately active against KBNP-0028 as compared with the positive control, zanamivir, respectively.

A new diarylheptanoid glycoside from the stem bark of Alnus hirsuta and protective effects of diarylheptanoid derivatives in human HepG2 cells

To search for secondary metabolites of Alnus hirsuta (Betulaceae), various chromatographic separations of the ethyl acetate soluble fraction of the stem bark of A. hirsuta led to the isolation of a new diarylheptanoid glycoside, (3R)-1,7-bis-(4-dihydroxyphenyl)-3-heptanol 3-O-β-D- glucopyranosyl(1→3)-β-D-xylopyranoside (13) and twelve diarylheptanoid derivatives, namely, oregonin (1), rubranoside A (2), hirsutanonol 5-O-β-D-glucopyranoside (3), rubranoside B (4), rubranoside C (5), hirsutanonol (6), hirsutenone (7), (5S)-O-methylhirsutanonol (8), platyphylloside (9), platyphyllonol 5-O-β-D-xylopyranoside (10), aceroside VII (11) and platyphyllenone (12). Isolates were assessed for their hepatoprotective effects against tert-butylhydroperoxide (t-BHP)-induced toxicity in HepG2 cells. Of these isolates, compounds 1 - 8 showed significant hepatoprotective effects on t-BHP-induced damage to HepG2 cells, with 8 exhibiting the greatest protective effect (50.7±3.7% at a concentration of 10 μM).

The Structures of Four Diarylheptanoid Glycosides from the Female Flowers of Alnus serrulatoides

Four diarylheptanoid monoglycosides (2a), (2b), (3), and (4), in addition to the hydroxy ketone (1), were isolated from the female flowers of Alnus serrulatoides.On the basis of the physicochemical and the X-ray crystallographic analyses, these were chara

THE ABSOLUTE CONFIGURATION OF DIARYLHEPTANOID XYLOSIDE, OREGONIN, ISOLATED FROM THE FEMALE FLOWERS OF ALNUS SERRULATOIDES

It was found that (-)-diarylheptanoid xyloside isolated from the female flowers of Alnus serrulatoides is 1,7-bis(3,4-dihydroxyphenyl)-5-(β-D-xylopyranosyloxy)-3-heptanone, and its spectral data and chemical behaviors coincides perfectly with those of previously reported oregonin whose absolute configuration had not been clarified yet.Then, the absolute configuration of the diarylheptanoid xyloside was investigated by a combination of the 13C NMR spectroscopy and the X-ray crystallography, and established to be S.