- Reductive α-substitution of sulfoxides with grignard reagents promoted by a magnesium amide
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The reactions of sulfoxides bearing α-hydrogen(s) (RSOCHR1R2: R-alkyl or aryl; R1, R2 = H, alkyl, or aryl) with Grignard reagents (R3MgBr: R3 = Et, Ph, or vinyl) in the presence of the diisopropylaminomagnesium reagent, generated in situ by the treatment of diisopropylamine with the appropriate Grignard reagents in diethyl ether, have resulted in the formation of the corresponding sulfides (RSCR1R2R3) in moderate to good isolated yields.
- Kobayashi, Kazuhiro,Yokota, Kouichi,Akamatsu, Hideki,Morikawa, Osamu,Konishi, Hisatoshi
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p. 441 - 443
(2007/10/03)
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- A BIOMIMETIC SYNTHESIS OF CHRISANTEMOL
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The factors governing the competition between 1,2- and 1,3-eliminations have been studied and the results obtained have been applied to a biomimetic synthesis of chrysantemol.
- Babin, D.,Fourneron, J. D.,Harwood, L. M.,Julia, M.
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p. 325 - 332
(2007/10/02)
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