41743-44-6 Usage
Uses
Used in Pharmaceutical Industry:
FERUTININ is used as a pharmaceutical agent for its agonistic activity towards the estrogen receptor (ER) α. This property makes it potentially useful in the treatment of conditions related to estrogen deficiency or imbalance, such as menopausal symptoms, osteoporosis, and certain types of cancer.
Used in Cellular Research:
In cellular research, FERUTININ is used as a tool to study the effects of increased calcium permeability on various cellular structures, including mitochondria, thymocytes, sarcoplasmic reticulum, and liposomes. This can help researchers better understand the role of calcium in cellular processes and develop new therapeutic strategies for conditions involving calcium dysregulation.
Used in Drug Delivery Systems:
FERUTININ's ability to increase calcium permeability can be exploited in the development of novel drug delivery systems. By enhancing the permeability of cellular membranes, FERUTININ may facilitate the delivery of therapeutic agents into cells, potentially improving the efficacy and bioavailability of certain drugs.
Used in Cosmetics Industry:
In the cosmetics industry, FERUTININ may be used as an ingredient in anti-aging products due to its agonistic activity towards the estrogen receptor (ER) α. This could potentially help improve skin elasticity, reduce wrinkles, and provide other age-defying benefits.
Check Digit Verification of cas no
The CAS Registry Mumber 41743-44-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,7,4 and 3 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 41743-44:
(7*4)+(6*1)+(5*7)+(4*4)+(3*3)+(2*4)+(1*4)=106
106 % 10 = 6
So 41743-44-6 is a valid CAS Registry Number.
InChI:InChI=1/C22H30O4/c1-14(2)22(25)12-11-21(4)10-9-15(3)13-18(19(21)22)26-20(24)16-5-7-17(23)8-6-16/h5-9,14,18-19,23,25H,10-13H2,1-4H3/t18-,19+,21-,22+/m0/s1
41743-44-6Relevant articles and documents
Hemisynthesis, Antitumoral Effect, and Molecular Docking Studies of Ferutinin and Its Analogues
Safi, Rmi,Rodriguez, Frderic,Hilal, Georges,Diab-Assaf, Mona,Diab, Youssef,El-Sabban, Marwan,Najjar, Fadia,Delfourne, Evelyne
, p. 382 - 397 (2016/03/12)
The natural product ferutinin was shown to act as an agonist to estrogen receptor ERα and agonist/antagonist to ERβ featuring a weak antiproliferative activity toward breast cancer cells. To enhance this activity, ferutinin analogues were synthesized by e
PROSTANOIDS. LVIII. NEW α,ω-NORANALOGS OF PROSTAGLANDINS FROM FERUTINOL
Tolstikov, G. A.,Akbutina, F. A.,Dembitskii, A. D.,Valeev, F. A.,Miftakhov, M. S.
, p. 1666 - 1673 (2007/10/02)
The chemical transformations of ferutinol aimed at the construction of structures that are of pharmacological interest were studied.