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FERUTININ is a bioactive compound that exhibits agonistic activity towards the estrogen receptor (ER) α. It is known for its ability to increase the calcium permeability of various lipid bilayer membranes, including mitochondria, thymocytes, sarcoplasmic reticulum, and liposomes. This unique property makes FERUTININ a promising candidate for various applications in different industries.

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  • 3-hydroxy-3-isopropyl-6,8a-dimethyl-1,2,3a,4,5,8-hexahydroazulen-4-yl 4-hydroxybenzoate

    Cas No: 41743-44-6

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  • 41743-44-6 Structure
  • Basic information

    1. Product Name: FERUTININ
    2. Synonyms: FERUTININ;TEFESTROL;Ferutinin (high purity);Ferutinol p-hydroxybenzoate;Jaeschkeanadiol p-hydroxybenzoate
    3. CAS NO:41743-44-6
    4. Molecular Formula: C22H30O4
    5. Molecular Weight: 358.47
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 41743-44-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 489°C at 760 mmHg
    3. Flash Point: 164.4°C
    4. Appearance: /
    5. Density: 1.16g/cm3
    6. Vapor Pressure: 2.24E-10mmHg at 25°C
    7. Refractive Index: 1.573
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: FERUTININ(CAS DataBase Reference)
    11. NIST Chemistry Reference: FERUTININ(41743-44-6)
    12. EPA Substance Registry System: FERUTININ(41743-44-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 41743-44-6(Hazardous Substances Data)

41743-44-6 Usage

Uses

Used in Pharmaceutical Industry:
FERUTININ is used as a pharmaceutical agent for its agonistic activity towards the estrogen receptor (ER) α. This property makes it potentially useful in the treatment of conditions related to estrogen deficiency or imbalance, such as menopausal symptoms, osteoporosis, and certain types of cancer.
Used in Cellular Research:
In cellular research, FERUTININ is used as a tool to study the effects of increased calcium permeability on various cellular structures, including mitochondria, thymocytes, sarcoplasmic reticulum, and liposomes. This can help researchers better understand the role of calcium in cellular processes and develop new therapeutic strategies for conditions involving calcium dysregulation.
Used in Drug Delivery Systems:
FERUTININ's ability to increase calcium permeability can be exploited in the development of novel drug delivery systems. By enhancing the permeability of cellular membranes, FERUTININ may facilitate the delivery of therapeutic agents into cells, potentially improving the efficacy and bioavailability of certain drugs.
Used in Cosmetics Industry:
In the cosmetics industry, FERUTININ may be used as an ingredient in anti-aging products due to its agonistic activity towards the estrogen receptor (ER) α. This could potentially help improve skin elasticity, reduce wrinkles, and provide other age-defying benefits.

Check Digit Verification of cas no

The CAS Registry Mumber 41743-44-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,7,4 and 3 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 41743-44:
(7*4)+(6*1)+(5*7)+(4*4)+(3*3)+(2*4)+(1*4)=106
106 % 10 = 6
So 41743-44-6 is a valid CAS Registry Number.
InChI:InChI=1/C22H30O4/c1-14(2)22(25)12-11-21(4)10-9-15(3)13-18(19(21)22)26-20(24)16-5-7-17(23)8-6-16/h5-9,14,18-19,23,25H,10-13H2,1-4H3/t18-,19+,21-,22+/m0/s1

41743-44-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name FERUTININ

1.2 Other means of identification

Product number -
Other names Hecameg

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:41743-44-6 SDS

41743-44-6Relevant articles and documents

Hemisynthesis, Antitumoral Effect, and Molecular Docking Studies of Ferutinin and Its Analogues

Safi, Rmi,Rodriguez, Frderic,Hilal, Georges,Diab-Assaf, Mona,Diab, Youssef,El-Sabban, Marwan,Najjar, Fadia,Delfourne, Evelyne

, p. 382 - 397 (2016/03/12)

The natural product ferutinin was shown to act as an agonist to estrogen receptor ERα and agonist/antagonist to ERβ featuring a weak antiproliferative activity toward breast cancer cells. To enhance this activity, ferutinin analogues were synthesized by e

PROSTANOIDS. LVIII. NEW α,ω-NORANALOGS OF PROSTAGLANDINS FROM FERUTINOL

Tolstikov, G. A.,Akbutina, F. A.,Dembitskii, A. D.,Valeev, F. A.,Miftakhov, M. S.

, p. 1666 - 1673 (2007/10/02)

The chemical transformations of ferutinol aimed at the construction of structures that are of pharmacological interest were studied.

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