Welcome to LookChem.com Sign In|Join Free

CAS

  • or
(±)-Stemonamine is an alkaloid found as a minor constituent in the roots of Stemona japonica, occurring alongside its isomer, isostemonamine. It is separated from accompanying alkaloids using chromatography and countercurrent distribution methods. The structure of (±)-Stemonamine has been determined through X-ray crystallographic analysis of its hydrochloride dihydrate, which forms triclinic crystals in the space group P1 with dimensions a = 14.62, b = 9.29, and c = 7.74 ?. The structure was solved using a modified Fourier technique based on the heavy-atom positions.

41758-66-1 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 41758-66-1 Structure
  • Basic information

    1. Product Name: (±)-Stemonamine
    2. Synonyms: (±)-Stemonamine;rac-(8S*,8aS*)-3'-Methoxy-6,4'-dimethyl-1,8a-propano-1,2,3,4,5,7-hexahydrospiro[cyclopenta[b]azepine-8(8aH),2'(5'H)-furan]-7,5'-dione;Stemonamine
    3. CAS NO:41758-66-1
    4. Molecular Formula: C18H23NO4
    5. Molecular Weight: 317.37952
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 41758-66-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 564.8°Cat760mmHg
    3. Flash Point: 295.4°C
    4. Appearance: /
    5. Density: 1.27g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (±)-Stemonamine(CAS DataBase Reference)
    10. NIST Chemistry Reference: (±)-Stemonamine(41758-66-1)
    11. EPA Substance Registry System: (±)-Stemonamine(41758-66-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 41758-66-1(Hazardous Substances Data)

41758-66-1 Usage

Uses

1. Used in Pharmaceutical Industry:
(±)-Stemonamine is used as a pharmaceutical compound for its potential therapeutic applications. The expression is: (±)-Stemonamine is used as a pharmaceutical compound for its potential therapeutic applications.
2. Used in Research and Development:
(±)-Stemonamine is used as a research compound for studying its chemical properties, structure, and potential interactions with other molecules. The expression is: (±)-Stemonamine is used as a research compound for studying its chemical properties, structure, and potential interactions with other molecules.
3. Used in Drug Discovery:
(±)-Stemonamine can be used as a starting point for drug discovery, as its unique structure and properties may lead to the development of new therapeutic agents. The expression is: (±)-Stemonamine is used as a starting point for drug discovery, with its unique structure and properties potentially leading to the development of new therapeutic agents.
4. Used in Natural Product Chemistry:
(±)-Stemonamine serves as an example of a naturally occurring alkaloid, contributing to the understanding of the chemical diversity found in nature. The expression is: (±)-Stemonamine is used as an example of a naturally occurring alkaloid, contributing to the understanding of the chemical diversity found in nature.

Check Digit Verification of cas no

The CAS Registry Mumber 41758-66-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,7,5 and 8 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 41758-66:
(7*4)+(6*1)+(5*7)+(4*5)+(3*8)+(2*6)+(1*6)=131
131 % 10 = 1
So 41758-66-1 is a valid CAS Registry Number.

41758-66-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name Isostemonamine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:41758-66-1 SDS

41758-66-1Upstream product

41758-66-1Downstream Products

41758-66-1Relevant articles and documents

Asymmetric Total Synthesis of (?)-Stemonamine and Its Stereochemical Stability

Fujita, Satoshi,Nishikawa, Keisuke,Iwata, Takayuki,Tomiyama, Taishi,Ikenaga, Hiroshi,Matsumoto, Kenji,Shindo, Mitsuru

, p. 1539 - 1543 (2018)

The first asymmetric total synthesis of (?)-stemonamine is described. The key reactions included intramolecular acylation to construct the seven-membered ring and a tandem [2+2] cycloaddition-Dieckmann condensation reaction using an ynolate to form the fully substituted cyclopentenone moiety. Racemization and epimerization of the natural product were first experimentally demonstrated.

First asymmetric total synthesis of (?)-isostemonamine and kinetic analysis of its isomerizations

Iwata, Takayuki,Tomiyama, Taishi,Fujita, Satoshi,Shindo, Mitsuru

, p. 712 - 718 (2019/04/26)

The first asymmetric total synthesis of (?)-isostemonamine is reported herein. The key reactions include the regioselective oxidation of the diketone, which is reported to be an intermediate in our synthesis of (?)-stemonamine. The chiral high-performance liquid chromatography (HPLC) analysis of the racemization and epimerization of (?)-isostemonamine revealed that isostemonamine isomerizes significantly faster than stemonamine.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 41758-66-1