41863-30-3

Basic information

• Product Name: sodium DL-methionate
• Synonyms: sodium DL-methionate;DL-Methionin, Natriumsalz;(±)-Methionine sodium;DL-Methionine sodium
• CAS NO: 41863-30-3
• Molecular Formula: C₅H₁₀NO₂S*Na
• Molecular Weight: 171.19317
• EINECS: 255-568-4
• Mol File: 41863-30-3.mol

Chemical Properties

• Boiling Point: 306.9°C at 760 mmHg
• Flash Point: 139.4°C
• Appearance: /
• Vapor Pressure: 0.00017mmHg at 25°C
• CAS DataBase Reference: sodium DL-methionate(CAS DataBase Reference)
• NIST Chemistry Reference: sodium DL-methionate(41863-30-3)
• EPA Substance Registry System: sodium DL-methionate(41863-30-3)

Safety Data

• Hazardous Substances Data: 41863-30-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C5H11NO2S.Na/c1-9-3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8);/q;+1/p-1

Upstream product

• 19298-72-7 DL-methionine amide 
• 13253-44-6 5-[2-(methylthio)ethyl]imidazolidine-2,4-dione 

Downstream Products

• 1115-47-5 N-acetyl-DL-methionine 
• 59-51-8 DL-methionine 
• 87459-76-5 N-(3-benzoilmercaptopropionil)-DL-metionina 

Relevant articles and documents

METHOD FOR MAKING METHIONINE

The invention concerns a continuous process for manufacturing methionine by alkaline hydrolysis of methionine hydantoin in aqueous phase, removing NH3 and CO2 of the hydrolysis medium, and neutralizing the obtained methioninate salt, according to which, after removal of NH3 and CO2, the hydrolysis reaction medium is concentrated to precipitate Na2CO3, said Na2CO3 being separated then recycled for alkaline hydrolysis, the latter being carried out in the presence of NaOH and Na2CO3.

A process for the preparation of L-methionine

The invention aims to the field of chemical engineering, and relates to a method for preparing L-methionine. According to the method, acetylated saponification liquid is used as production raw material, acid is added into the raw material, the pH is adjusted to be acidic, after reduced pressure distillation, an organic solvent is used for treatment, so that a solution containing D,L-acetyl methionine is obtained, then the organic solvent is removed to obtain D,L-acetyl methionine crystals, and a resolution reaction is performed on the produced D,L-acetyl methionine crystals, so that the L-methionine is obtained; the technology does not need refined D,L-methionine, the soponification liquid for producing the D,L-methionine is used for performing an acetylated reaction, and therefore production cost is reduced; after the acetylation, water is evaporated to dryness, the organic solvent is used for desalting, the yield of the D,L-acetyl methionine reaches 97-99%, and the purity of the D,L-acetyl methionine reaches above 96%; the enzymolysis speed of the D,L-acetyl methionine is higher than that of a traditional method, the obtained L-methionine is good in crystal form and whiteness, the purity reaches above 99.5%, and the total yield of the L-methionine is improved to 78%; according to the technology, a circulation technology is integrated, the design is reasonable, and production cost is reduced.

Method for the continuous preparation of methionine or methionine derivatives

The direct saponification of methionine nitrile obtained from methylmercaptopropionaldehyde, prussic acid and ammonia gives low yields, catalyst and educt losses and unwanted side-products. The aim of the invention is therefore to provide a method which can be carried out without isolating the intermediate products, in particular continuously, and with low losses. The ketone used is recovered in high yields after amide saponification since this liberates the ketone from side-products. In order to recover the ammonia, it is necessary for the ammonia to be substantially freed of ketone, the mixture of ammonia, ketone and water obtained being separated under pressure in a separation column. When the amide is saponified at ≥160° C., amide concentrations of less than 25% by wt. are preferred. Methionine nitrile is produced by treatment with at least 4 equivalents of ≥50% by wt. ammonia at between 40° and 80° C./or between 5 and 60 min. Cyanide residues are destroyed by heating to over 150° C. Methionine is of particular use as a feedstuff, in particular in aqueous solution.