420808-42-0Relevant articles and documents
Synthesis, spectral and antimicrobial studies of some N(2)-Substituted tetrahydroindazoles
Amirthaganesan, Shanmugasundaram,Aridoss, Gopalakrishnan,Park, Keun Soo,Lim, Kwon Taek,Jeong, Yeon Tae
experimental part, p. 1135 - 1142 (2010/10/04)
A series of N(2)-benzothiazolyl substituted tetrahydroindazoles has been synthesized via cyclic β keto esters. Optimum reaction condition was found as acidic toluene and effect of higher acidity towards substituted hydrazines in situ was described. Synthe
COMPOUNDS AND PROCESS TO PREPARE CHIRAL INTERMEDIATES FOR SYNTHESIS OF PAROXETINE
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Page/Page column 100, (2009/03/07)
Provided herein are compounds and processes that produce intermediates and precursors of paroxetine and related compounds. Also provided are processes for the preparation of paroxetine.
Synthesis and1H and13C NMR spectral study of some t(3)-aryl-r(2),c(4)-dicarbalkoxy-c(5)-hydroxy-t(5)-methylcyclohexanones and their oximes
Amirthaganesan,Sabapathy Mohan,Murugavel,Muthukumaran,Pandiarajan
, p. 1004 - 1013 (2008/09/18)
Eight t(3)-aryl-r(2),c(4)-bis(carbalkoxy)-c(5)-hydroxy-t(5)- methylcyclohexanone oximes 4a (Ar = Ph; R = Et), 5a (Ar = p-NO2C 6H4; R = Et), 6a (Ar = p-ClC6H4; R = Et), 7a (Ar = Ph; R = Me), 8a (Ar =p-
Reaction of aromatic aldehydes with β-dicarbonyl compounds in a catalytic system: Piperidinium acetate - 1-butyl-3-methylimidazolium tetrafluoroborate ionic liquid
Putilova,Troitskii,Zlotin
, p. 1233 - 1238 (2007/10/03)
Condensation of aromatic (heteroaromatic) aldehydes with 1,3-dicarbonyl compounds under the 1-butyl-3-methylimidazolium tetrafluoroborate ([Bmim][BF4]) ionic liquid - piperidinium acetate catalytic system (0.2 equiv. of each component) in the absence of a solvent affords, depending on the structures of the reagents, 2-arylidene derivatives of methyl acetoacetate and acetylacetone, diethyl 2,4-bis(trifluoroacetyl)-3-phenylpentanedioate, or dimethyl 2-aryl-4-hydroxy-6-oxocyclohexane-1,3-dicarboxylates. The reactions of the resulting 2-arylidene derivatives with O-methylisourea in the [Bmim][BF 4] ionic liquid produced methyl 2-methoxy-4-methyl-6- aryldihydropyrimidine-5-carboxylates and 1-(2-methoxy-4-methyl-6- phenyldihydropyrimidin-5-yl)ethanone (mixtures of 3,6- and 1,6-dihydro isomers), which were transformed into the corresponding 3,4-dihydropyrimidin-2(1H)-one derivatives.