42482-68-8 Usage
Uses
Used in Pharmaceutical Industry:
(18α,19α)-Urs-20-ene-3,16-dione is used as a pharmaceutical agent for its diverse range of biological activities. Its anti-inflammatory properties make it a candidate for treating inflammatory conditions, while its anti-cancer effects suggest potential in combating cancer cells and enhancing the efficacy of conventional cancer therapies.
Used in Medicinal Applications:
In the medicinal field, (18α,19α)-Urs-20-ene-3,16-dione is utilized for its anti-diabetic activity, which may help in managing blood sugar levels and improving overall glucose metabolism. Additionally, its wound healing promotion makes it a valuable component in treatments aimed at accelerating the healing process and improving skin health.
Used in Cholesterol Management:
(18α,19α)-Urs-20-ene-3,16-dione is used as a cholesterol-lowering agent, contributing to cardiovascular health by reducing harmful cholesterol levels and potentially decreasing the risk of heart disease.
As research progresses, the potential applications of (18α,19α)-Urs-20-ene-3,16-dione may expand, offering new avenues for treatment and therapeutic intervention across various health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 42482-68-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,4,8 and 2 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 42482-68:
(7*4)+(6*2)+(5*4)+(4*8)+(3*2)+(2*6)+(1*8)=118
118 % 10 = 8
So 42482-68-8 is a valid CAS Registry Number.
InChI:InChI=1/C30H46O2/c1-18-11-14-28(6)24(32)17-30(8)20(25(28)19(18)2)9-10-22-27(5)15-13-23(31)26(3,4)21(27)12-16-29(22,30)7/h11,19-22,25H,9-10,12-17H2,1-8H3
42482-68-8Relevant articles and documents
Cytotoxic and Apoptosis-inducing Activities of Taraxastane-type Triterpenoid Derivatives in Human Cancer Cell Lines
Ukiya, Motohiko,Ohkubo, Chika,Kurita, Masahiro,Fukatsu, Makoto,Suzuki, Takashi,Akihisa, Toshihiro
, p. 1018 - 1029 (2016)
Twenty-eight taraxastane-type triterpenoid derivatives 4?–?31 were prepared from the naturally occurring triterpenoids faradiol (1) and heliantriol C (3). The cytotoxic activities of these compounds and arnidiol (2) were evaluated in leukemia (HL60), lung (A549), duodenal (AZ521), and breast (SK-BR-3) cancer cell lines. 21-Oxoarnidiol (18) and faradiol 3,16-di-O-l-alaninate (31) exhibited potent cytotoxicity, with 50% inhibitory concentrations of 0.5?–?2.7?μm. In particular, flow cytometric analysis indicated that compound 31 induced typical apoptotic cell death in HL60 cells. These results suggested that taraxastane-type triterpenoid derivatives might provide useful antitumor agents with apoptosis-inducing activity.
