4250-90-2

Basic information

• Product Name: 7,8-dimethyl-10-formylmethylisoalloxazine
• Synonyms: 7,8-dimethyl-10-formylmethylisoalloxazine;10-(Formylmethyl)-7,8-dimethylisoalloxazine;3,4-Dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridine-10(2H)-acetaldehyde;6,7-Dimethyl-9-formylmethylisoalloxazine;7,8-Dimethyl-10-(2-oxoethyl)benzo[g]pteridine-2,4(3H,10H)-dione;7,8-Dimethyl-10-isoalloxazineacetaldehyde;Formylmethylflavine
• CAS NO: 4250-90-2
• Molecular Formula: C₁₄H₁₂N₄O₃
• Molecular Weight: 284.27
• Mol File: 4250-90-2.mol

Chemical Properties

• Appearance: /
• Density: 1.51g/cm³
• Refractive Index: 1.728
• CAS DataBase Reference: 7,8-dimethyl-10-formylmethylisoalloxazine(CAS DataBase Reference)
• NIST Chemistry Reference: 7,8-dimethyl-10-formylmethylisoalloxazine(4250-90-2)
• EPA Substance Registry System: 7,8-dimethyl-10-formylmethylisoalloxazine(4250-90-2)

Safety Data

• Hazardous Substances Data: 4250-90-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H12N4O3/c1-7-5-9-10(6-8(7)2)18(3-4-19)12-11(15-9)13(20)17-14(21)16-12/h4-6H,3H2,1-2H3,(H,17,20,21)

Upstream product

• 83-88-5 riboflavin 

Downstream Products

• 1086-80-2 lumichrome 
• 1088-56-8 lumiflavin 
• 1207984-64-2 10-(2-(3,4-dichIorobenzylamino)ethyl)-7,8-dimethyIbenzo[g]pteridine-2,4(3H,10H)-dione 
• 1207984-31-3 4-((2-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)ethylamino)methyl)benzoic acid 
• 1207984-13-1 tert-butyl 2-(2-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)ethylamino)benzoate 
• 1262314-94-2 N-(4-((2-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)ethyl)amino)phenyl)acetamide 
• 1262314-97-5 N-(4-chlorobenzyl)-2-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)acetamide 
• 21079-31-2 carboxylmethylflavin 
• 1207984-12-0 2-(2-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)ethylamino)benzoic acid 
• 1207984-66-4 tert-butyl 3,4-dichlorobenzyl(2-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)ethyl)carbamate 

Relevant articles and documents

Photoirradiation products of flavin derivatives, and the effects of photooxidation on guanine

Photoirradiation in the presence of riboflavin led to guanine oxidation and the formation of imidazolone. Meanwhile, riboflavin itself was degraded by ultraviolet light A (UV-A) and visible light (VIS) radiation, and the end product was lumichrome. VIS radiation in the presence of riboflavin oxidized guanine similarly to UV-A radiation. Although UV-A radiation with lumichrome oxidized guanine, VIS radiation with lumichrome did not. Thus, UV-A radiation with riboflavin can oxidize guanine even if riboflavin is degraded to lumichrome. In contrast, following VIS radiation degradation of riboflavin to lumichrome, VIS radiation with riboflavin is hardly capable of oxidizing guanine. The consequences of riboflavin degradation and guanine photooxidation can be extended to flavin mononucleotide and flavin adenine dinucleotide. In addition, we report advanced synthesis; carboxymethylflavin was obtained by oxidation of formylmethylflavin with chlorite and hydrogen peroxide; lumichrome was obtained by heating of formylmethylflavin in 50% AcOH; lumiflavin was obtained by incubation of formylmethylflavin in 2 M NaOH, followed by isolation by step-by-step concentration.

Effect of caffeine complexation on the photolysis of riboflavin in aqueous solution: A kinetic study

The effect of caffeine complexation with riboflavin on the kinetics of riboflavin photolysis in the pH range 2.0-10.5 has been studied. The photolysis of riboflavin solutions (5×10-5 M) was carried out in the presence of caffeine (0.5-2.5x10su