425604-51-9

Basic information

• Product Name: 2-[3-CYANO-4-(4-FLUOROPHENYL)-5,5-DIMETHYL-5H-FURAN-2-YLIDENE]MALONONITRILE
• Synonyms: 2-[3-CYANO-4-(4-FLUOROPHENYL)-5,5-DIMETHYL-5H-FURAN-2-YLIDENE]MALONONITRILE
• CAS NO: 425604-51-9
• Molecular Formula: C₁₆H₁₀FN₃O
• Molecular Weight: 279.27
• Mol File: 425604-51-9.mol

Chemical Properties

• Boiling Point: 337.1°Cat760mmHg
• Flash Point: 157.6°C
• Appearance: /
• Density: 1.3g/cm³
• Vapor Pressure: 0.000108mmHg at 25°C
• Refractive Index: 1.584
• CAS DataBase Reference: 2-[3-CYANO-4-(4-FLUOROPHENYL)-5,5-DIMETHYL-5H-FURAN-2-YLIDENE]MALONONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[3-CYANO-4-(4-FLUOROPHENYL)-5,5-DIMETHYL-5H-FURAN-2-YLIDENE]MALONONITRILE(425604-51-9)
• EPA Substance Registry System: 2-[3-CYANO-4-(4-FLUOROPHENYL)-5,5-DIMETHYL-5H-FURAN-2-YLIDENE]MALONONITRILE(425604-51-9)

Safety Data

• Hazardous Substances Data: 425604-51-9(Hazardous Substances Data)

Usage

Structure

Consists of a furan ring with a cyano group and a fluorophenyl group attached to it, along with a malononitrile moiety.

Furan Ring

Contains a cyano group (CN) and a 4-fluorophenyl group attached at the 3rd position.

Malononitrile Moiety

Carbonitrile group (-C≡N) attached to the furan ring.

Functional Groups

Cyano (CN), Fluorophenyl (C6H4F), Carbonitrile (-C≡N).

Substituents

Methyl groups (CH3) at the 5th position of the furan ring.

Potential Use

Reagent or intermediate in organic synthesis.

Properties

Requires further investigation and testing for specific physical and chemical properties.
Likely exhibits reactivity typical of compounds containing cyano and phenyl groups.

Applications

Potential utility in pharmaceuticals, agrochemicals, or materials science.
May serve as a building block in the synthesis of more complex organic compounds.

Further Investigation

Analysis of its reactivity under various conditions.
Examination of its potential toxicity and environmental impact.
Assessment of its stability and compatibility with other compounds in different reaction environments.

InChI:InChI=1/C16H10FN3O/c1-16(2)14(10-3-5-12(17)6-4-10)13(9-20)15(21-16)11(7-18)8-19/h3-6H,1-2H3

Upstream product

• 460-00-4 1-Bromo-4-fluorobenzene 
• 335287-91-7 1-(4-fluorophenyl)-2-hydroxy-2-methylpropan-1-one 
• 109-77-3 malononitrile 

Downstream Products

• 481642-77-7 2-[3-Cyano-4-(4-dioctylamino-phenyl)-5,5-dimethyl-5H-furan-2-ylidene]-malononitrile 
• 821789-33-7 2-[4-(4-Azepan-1-yl-phenyl)-3-cyano-5,5-dimethyl-5H-furan-2-ylidene]-malononitrile 
• 821789-34-8 2-{3-Cyano-4-[4-(3,5-dimethyl-piperidin-1-yl)-phenyl]-5,5-dimethyl-5H-furan-2-ylidene}-malononitrile 
• 888069-41-8 C₂₁H₂₃N₅O 
• 913733-36-5 2-[3-cyano-4-(4-{[6-(3,5-dioxo-10-oxa-4-aza-tricyclo[5.2.1.0^2,6]dec-8-en-4-yl)-hexyl]-propyl-amino}-phenyl)-5,5-dimethyl-5H-furan-2-ylidene]-malononitrile 

Relevant articles and documents

Fluorescence microscopy visualization of contacts between objects

The area of contact between two objects was detected by using the strong enhancement of the fluorescence of rigidochromic probe molecules attached to one of the surfaces. Confinement of the molecules suppresses nonradiative decay and turns on the fluorescence. The approach is demonstrated by imaging of the contact area of a plastic sphere in contact with a flat glass surface. Our results agree excellently with the prediction of Hertz's classical theory based on elastic deformation. All the fun of the surface: By using rigidochromic fluorescent probe molecules attached to a surface, the contact area between the surface and an object can be visualized. Confinement of the molecules suppresses nonradiative decay and turns on the fluorescence.

Fluorophore compounds and their use in biological systems

Fluorophore compounds and methods for their use are disclosed. The fluorophores contain a 2-dicyanomethylen-3-cyano-2,5-dihydrofuran (DCDHF) moiety and one or more donor groups conjugated to the 2-dicyanomethylen-3-cyano-2,5-dihydrofuran group. The donor