428816-43-7 Usage
Uses
Used in Pharmaceutical Industry:
5-[Isocyano-(toluene-4-sulfonyl)-methyl]-benzo[1,3]dioxole is used as a reagent in the synthesis of various pharmaceuticals. Its unique structure allows for the creation of diverse drug molecules with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 5-[Isocyano-(toluene-4-sulfonyl)-methyl]-benzo[1,3]dioxole is utilized as a reagent for the preparation of agrochemicals. Its ability to form various chemical structures makes it valuable in developing new compounds for agricultural use.
Safety Precautions:
It is important to handle 5-[Isocyano-(toluene-4-sulfonyl)-methyl]-benzo[1,3]dioxole with care, as it is a toxic compound. Exposure to skin or inhalation can be harmful, so proper safety measures should be taken during its use and storage.
Check Digit Verification of cas no
The CAS Registry Mumber 428816-43-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,2,8,8,1 and 6 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 428816-43:
(8*4)+(7*2)+(6*8)+(5*8)+(4*1)+(3*6)+(2*4)+(1*3)=167
167 % 10 = 7
So 428816-43-7 is a valid CAS Registry Number.
InChI:InChI=1/C16H13NO4S/c1-11-3-6-13(7-4-11)22(18,19)16(17-2)12-5-8-14-15(9-12)21-10-20-14/h3-9,16H,10H2,1H3
428816-43-7Relevant articles and documents
Design and modular parallel synthesis of a MCR derived α-helix mimetic protein-protein interaction inhibitor scaffold
Antuch, Walfrido,Menon, Sanjay,Chen, Quin-Zene,Lu, Yingchun,Sakamuri, Sukumar,Beck, Barbara,Schauer-Vukasinovic, Vesna,Agarwal, Seema,Hess, Sibylle,Doemling, Alexander
, p. 1740 - 1743 (2007/10/03)
A terphenyl α-helix mimetic scaffold recognized to be capable of disrupting protein-protein interactions was structurally morphed into an easily amenable and versatile multicomponent reaction (MCR) backbone. The design, modular in-parallel library synthes
NOVEL TRIAZOLE AND OXAZOLE COMPOUNDS AS TRANSFORMING GROWTH FACTOR (TGF) INHIBITOR
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Page 49, (2008/06/13)
Novel oxazole and thiazole compounds, including derivatives thereof, to intermediates for their preparation, to pharmaceutical compositions containing them and to their medicinal use are described. The compounds of the present invention are potent inhibitors of transforming growth factor ("TGF")-β signaling pathway. They are useful in the treatment of various TGF-related disease states including, for example, cancer and fibrotic diseases.
