- Thio hydantoin ternary and circular androgen receptor antagonists and use thereof (by machine translation)
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The invention relates to the field of pharmaceutical chemistry, and in particular relates to a category of thio hydantoin and indoline skeleton has the role of the anti-prostate cancer compound (I) and (II), a method for preparing these compounds, these c
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Paragraph 0193; 0220; 0221
(2017/08/02)
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- 6-HETEROARYLOXY- OR 6-ARYLOXY-QUINOLINE-2-CARBOXAMIDES AND METHOD OF USE
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Compounds of formula (I) and pharmaceutically acceptable salts, esters, amides, or radiolabelled forms thereof, wherein R1, R2, and R3 are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by voltage-gated sodium channels, e.g., Nav1.7 and/or Nav1.8. Methods for making the compounds are disclosed. Also disclosed are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.
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- Bicyclo 4.4.0 antiviral derivatives
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This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with amido piperazine derivatives. These compounds possess unique antiviral activity
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Page/Page column 32
(2008/06/13)
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- Heterocycle annulation of enolizable vinyl quinone imides. Dihydroquinolines and quinolines from thermal 6π-electrocyclizations and indoles from photochemical cyclizations
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(equation presented) Enolizable vinyl quinone mono-and diimide substrates yield protected 6-hydroxy and 6-amino dihydroquinolines by thermal electrocyclization. Aromatization provides the corresponding quinolines in quantitative yields. The quinone monoimide substrates undergo clean photochemical conversion to 5-hydroxy indoles.
- Parker, Kathlyn A.,Mindt, Thomas L.
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p. 4265 - 4268
(2007/10/03)
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