The direct synthesis of isoflavans VIA α-alkylation of phenylacetates
Deprotonation of oxygenated phenylacetates and quenching of the enolates with oxygenated benzylic electrophiles, afforded 2,3-diarylpropanoates which served as precursors to the isoflavans following consecutive reduction and cyclization steps.
Versteeg, Marietjie,Bezuidenhoudt, Barend C. B.,Ferreira, Daneel
p. 1373 - 1394
(2007/10/03)
THE FIRST DIRECT SYNTHESIS OF ISOFLAVANS VIA α-ALKYLATION OF PHENYLACETATES
Deprotonation of phenylacetates and quenching of the enolates with benzylic electrophiles, afford 2,3-diarylpropanoates which serve as precursors to isoflavans following consecutive reduction and cyclization steps.
Versteeg, Marietjie,Bezuidenhoudt, Barend C. B.,Ferreira, Daneel
p. 1743 - 1746
(2007/10/02)
TRANSFORMATION DU CATION ISOFLAVYLIUM EN PHENYL-3 COUMARINES, ISOFLAVENES-3 ET ISOFLAVANNES
Isoflavylium salts 1 are key starting materials for synthesis of 3-phenyl coumarins 2,isoflav-3-enes 4 and isoflavans 5, by chemical conversions narrowsly apparented to biogenetic pathways actually recognized for natural compounds of these series.