431980-51-7 Usage
Uses
Used in Organic Synthesis:
2,5-DIMETHYL-1-PYRIDIN-4-YL-1H-PYRROLE-3-CARBALDEHYDE is used as a building block in organic synthesis for its unique structure and reactivity, facilitating the creation of new compounds with potential applications across various industries.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2,5-DIMETHYL-1-PYRIDIN-4-YL-1H-PYRROLE-3-CARBALDEHYDE is utilized as a key intermediate in the development of new drugs. Its distinctive molecular architecture allows for the exploration of novel therapeutic agents with potential medicinal properties.
Used in Agrochemical Development:
2,5-DIMETHYL-1-PYRIDIN-4-YL-1H-PYRROLE-3-CARBALDEHYDE is also employed in the agrochemical sector as a component in the synthesis of new pesticides or other agricultural chemicals, leveraging its reactive nature to create effective and innovative products.
Used in Materials Science:
In the field of materials science, 2,5-DIMETHYL-1-PYRIDIN-4-YL-1H-PYRROLE-3-CARBALDEHYDE is used as a component in the development of new materials, potentially contributing to advances in areas such as polymers, sensors, or other high-tech applications.
Used as a Molecular Probe in Biological and Biochemical Studies:
2,5-DIMETHYL-1-PYRIDIN-4-YL-1H-PYRROLE-3-CARBALDEHYDE may have biological activity, and as such, it is used as a molecular probe in biological and biochemical research. This application is aimed at understanding its interactions with biological systems, which could reveal new insights into its properties and potential uses.
Check Digit Verification of cas no
The CAS Registry Mumber 431980-51-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,3,1,9,8 and 0 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 431980-51:
(8*4)+(7*3)+(6*1)+(5*9)+(4*8)+(3*0)+(2*5)+(1*1)=147
147 % 10 = 7
So 431980-51-7 is a valid CAS Registry Number.
431980-51-7Relevant articles and documents
Discovery and structure-activity relationships of pyrrolone antimalarials
Murugesan, Dinakaran,Mital, Alka,Kaiser, Marcel,Shackleford, David M.,Morizzi, Julia,Katneni, Kasiram,Campbell, Michael,Hudson, Alan,Charman, Susan A.,Yeates, Clive,Gilbert, Ian H.
, p. 2975 - 2990 (2013/05/23)
In the pursuit of new antimalarial leads, a phenotypic screening of various commercially sourced compound libraries was undertaken by the World Health Organisation Programme for Research and Training in Tropical Diseases (WHO-TDR). We report here the detailed characterization of one of the hits from this process, TDR32750 (8a), which showed potent activity against Plasmodium falciparum K1 (EC50 ～ 9 nM), good selectivity (>2000-fold) compared to a mammalian cell line (L6), and significant activity against a rodent model of malaria when administered intraperitoneally. Structure-activity relationship studies have indicated ways in which the molecule could be optimized. This compound represents an exciting start point for a drug discovery program for the development of a novel antimalarial.
