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2,4-BIS(TRIFLUOROMETHYL)PHENACYL BROMIDE is a chemical compound that is widely utilized in organic synthesis and pharmaceutical research. It is recognized for its potent electrophilic properties, which allow it to activate aromatic compounds for nucleophilic aromatic substitution reactions. This reactivity makes it a valuable component in the creation of various pharmaceuticals, agrochemicals, and organic compounds with biological activity. Due to its high reactivity, it is essential to handle 2,4-BIS(TRIFLUOROMETHYL)PHENACYL BROMIDE with caution in a controlled laboratory environment.

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  • 435271-21-9 Structure
  • Basic information

    1. Product Name: 2,4-BIS(TRIFLUOROMETHYL)PHENACYL BROMIDE
    2. Synonyms: 2',4'-BIS(TRIFLUOROMETHYL)-2-BROMOACETOPHENONE;2,4-BIS(TRIFLUOROMETHYL)PHENACYL BROMIDE;2',4'-Bis(trifluoromethyl)-2-bromoacetophenone, 1-[2,4-Bis(trifluoromethyl)phenyl]-2-bromoethan-1-one;1-[2,4-bis(trifluoromethyl)phenyl]-2-bromoethanone
    3. CAS NO:435271-21-9
    4. Molecular Formula: C10H5BrF6O
    5. Molecular Weight: 335.04
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 435271-21-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 259.6±40.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.665±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2,4-BIS(TRIFLUOROMETHYL)PHENACYL BROMIDE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2,4-BIS(TRIFLUOROMETHYL)PHENACYL BROMIDE(435271-21-9)
    11. EPA Substance Registry System: 2,4-BIS(TRIFLUOROMETHYL)PHENACYL BROMIDE(435271-21-9)
  • Safety Data

    1. Hazard Codes: C
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 435271-21-9(Hazardous Substances Data)

435271-21-9 Usage

Uses

Used in Organic Synthesis:
2,4-BIS(TRIFLUOROMETHYL)PHENACYL BROMIDE is used as an electrophilic reagent for the activation of aromatic compounds, facilitating nucleophilic aromatic substitution reactions. This application is crucial in the synthesis of complex organic molecules and contributes to the development of new chemical entities.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2,4-BIS(TRIFLUOROMETHYL)PHENACYL BROMIDE is employed as a key intermediate in the production of various pharmaceuticals. Its ability to participate in substitution reactions aids in the synthesis of drug molecules with potential therapeutic applications.
Used in Agrochemical Production:
2,4-BIS(TRIFLUOROMETHYL)PHENACYL BROMIDE is used as a building block in the synthesis of agrochemicals, such as pesticides and herbicides. Its reactivity in organic synthesis allows for the creation of compounds that can be used to protect crops from pests and diseases.
Used in the Synthesis of Biologically Active Compounds:
This chemical compound is also utilized in the synthesis of organic compounds with biological activity. The resulting molecules may have potential applications in various fields, such as medicine, biotechnology, and materials science, where they could be used to develop new therapeutic agents or functional materials.

Check Digit Verification of cas no

The CAS Registry Mumber 435271-21-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,3,5,2,7 and 1 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 435271-21:
(8*4)+(7*3)+(6*5)+(5*2)+(4*7)+(3*1)+(2*2)+(1*1)=129
129 % 10 = 9
So 435271-21-9 is a valid CAS Registry Number.

435271-21-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[2,4-Bis(trifluoromethyl)phenyl]-2-bromoethanone

1.2 Other means of identification

Product number -
Other names PC8402

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:435271-21-9 SDS

435271-21-9Upstream product

435271-21-9Downstream Products

435271-21-9Relevant articles and documents

SUBSTITUTED THIAZOLE DERIVATIVES BEARING 3-PYRIDYL GROUPS, PROCESS FOR PREPARING THE SAME AND USE THEREOF

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Page/Page column 35, (2008/06/13)

The present invention provides a pharmaceutical composition having a steroid C17,20-lyase inhibitory activity, which is useful as a prophylactic or therapeutic agent of prostatism, tumor such as breast cancer and the like, more particularly, a steroid C17,20-lyase inhibitor containing a compound represented by the formula: wherein A1 is an aromatic hydrocarbon group optionally having substituents or a heterocyclic group optionally having substituents, one of A2 and A3 is a hydrogen atom, a halogen atom, a C1-4 aliphatic hydrocarbon group optionally having substituents or an optionally esterified carboxyl group, the other of A2 and A3 is an aromatic hydrocarbon group optionally having substituents or a heterocyclic group optionally having substituents, and at least one of A1, A2 and A3 is a 3-pyridyl group optionally having substituents, or a salt thereof or a prodrug thereof.

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